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Toplam kayıt 9, listelenen: 1-9
Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model
(Springer Heidelberg, 2020)
Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ...
Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy
(Spandidos Publications, 2021)
The aim of the present study was to investigate the effect of dexpanthenol on nerve healing following neurorrhaphy in lacerated peripheral nerves. A total of 30 mature Sprague Dawley rats were used. Surgical sciatic nerve ...
Anti-Inflammatory and Anti-Fibrotic Effects of Ursodeoxycholic Acid in Streptozocin-Induced Diabetic Rats
(Kocaeli Derince Eğitim ve Araştırma Hastanesi, 2020)
INTRODUCTION: Diabetic cardiomyopathy is a consequence of free fatty acid oxidation, dysfunction in mitochondria, oxidative stress and diffuse myocardial fibrosis. We aimed to investigate the anti-inflammatory and anti-fibrotic ...
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
(TAYLOR & FRANCIS INC, 2021)
Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ...
The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy
(Taylor and Francis Ltd., 2021)
Diabetic neuropathy (DN) is the most common degenerative complication associated with Diabetes Mellitus. Despite widespread awareness about DN, the only effective treatments are blood glucose control and pain management. ...
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
(Korean Neurosurgical Society, 2021)
Objective: Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ...
An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
(Hindawi, 2021)
Purpose. The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. Methods. The study was conducted on twenty-four male rats. ...
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
(URKISH ASSOC TRAUMA EMERGENCY SURGERY, 2022)
BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ...
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia
(Springer, 2022)
Alzheimer's disease (AD) is by far the most common cause of cognitive impairment in older adults. Current treatments are entirely focused on the symptoms of AD. A complex etiology for AD has been proposed recently, in which ...