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Toplam kayıt 10, listelenen: 1-10
3-Pyridinylboronic acid normalizes the effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in zebrafish embryos
(Taylor & Francis Ltd, 2020)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that damages dopaminergic neurons. Zebrafish has been shown to be a suitable model organism to investigate the molecular pathways in the pathogenesis of ...
Comparison of ultrastructural changes and the anticarcinogenic effects of thymol and carvacrol on ovarian cancer cells: which is more effective?
(Taylor & Francis Inc, 2020)
Ovarian cancer is the seventh most common cancer worldwide in women. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isopropylphenol) ...
Evaluation of cytotoxic, apoptotic effects and phenolic compounds of sea cucumber Holothuria tubulosa (Gmelin, 1791) extracts
(Scientific Technical Research Council Turkey-Tubitak, 2020)
This study aimed to investigate the potential cytotoxic effects and phenolic contents of aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Mugla (Turkey) against different cancer cells for ...
Apoptotic effects of thymol, a novel monoterpene phenol, on different types of cancer
(Comenius Univ, 2020)
BACKGROUND: Cancer is a major public health problem in many areas of the world. Many anticancer drugs in current clinical use have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isop ...
Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
(Springer, 2021)
Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In the present study, we aimed to investigate ...
Apoptotic and Antiproliferative Effect of Gingiva Mesenchymal Stem Cells on Acute Leukemia T Cells
(GALENOS PUBL HOUSE, 2021)
BACKGROUND/AIMS
The aim of this study was to investigate the antiproliferative and apoptotic effect of gingiva-derived mesenchymal stem cells (GMSCs) on the Jurkal cells as I-cell acute lymphoblastic leukemia cell ...
Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions
(MDPI, 2022)
Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties, such as antioxidant, antidiabetic, ...
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)
Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ...
Licorice ( Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects
(Dove Press, 2022)
Cancer is a highly lethal disease, and its incidence has rapidly increased worldwide over the past few decades. Although chemotherapeutics and surgery are widely used in clinical settings, they are often insufficient to ...
Anticancer and apoptotic effects of a polysaccharide extract isolated from Lactarius chrysorrheus Fr. in HepG2 and PANC-1 cell lines
(Institut za Bioloska Istrazivanja, 2023)
Mushrooms are widely used in many cultures for nutritional and health benefits. The Lactarius species is found in the Aegean region of Turkey. Lactarius chrysorrheus Fr. is a wild mushroom that contains a milky juice. In ...