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Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
(Sage Publications Ltd, 2020)
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer ...
Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
(Mdpi, 2019)
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ...
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
(Elsevier, 2021)
Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ...
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)
Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ...
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
(SPRINGER HEIDELBERG, 2022)
Nanotechnology has encouraged new and amended materials (metal nanoparticles) for therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) are versatile nanoscale entities, widely used to ...
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)
As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...