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Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
(Sage Publications Ltd, 2020)
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer ...
Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
(Mdpi, 2019)
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ...
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)
Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ...
NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target
(Elsevier, 2021)
Notch signaling, an evolutionarily conserved signaling cascade, is critical for normal biological processes of cell differentiation, development, and homeostasis. Deregulation of the Notch signaling pathway has been ...
Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments
(TAYLOR & FRANCIS INC, 2022)
Bee venom therapy is known as a traditional approach to curing many medical conditions such as arthritis, pain and rheumatism. Bee venom also provides promising potential for treating many cancers such as breast, lung, ...
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)
As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
(Springer Science and Business Media Deutschland GmbH, 2023)
Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ...