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Toplam kayıt 13, listelenen: 1-10
3-Pyridinylboronic acid normalizes the effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in zebrafish embryos
(Taylor & Francis Ltd, 2020)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that damages dopaminergic neurons. Zebrafish has been shown to be a suitable model organism to investigate the molecular pathways in the pathogenesis of ...
ANTIFUNGAL ACTIVITY OF CURCUMIN CASPOFUNGIN COMBINATION AGAINST CANDIDA SPP. VIA APOPTOTIC INDUCTION
(Parlar Scientific Publications (P S P), 2018)
Phytochemicals with drug combinations have led to the discovery of different therapeutics used in fighting off the different types of infections. In this study, I have investigated the synergetic antifungal effect of ...
The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144
(Springer, 2019)
Melanoma is a cancer of melanocyte cells and has the highest global incidence. There is a need to develop new drugs for the treatment of this deadly cancer, which is resistant to currently used treatment modalities. We ...
Evaluation of serum M30 and M65 activity in patients with stage-I endometrial cancer
(Taylor & Francis Inc, 2019)
We aimed to analyse the prognostic value of serum oxidative stress parameters and apoptotic markers of serum M30/65 levels in endometrial cancer patients. Serum M30/65 levels and oxidative stress parameters were evaluated ...
Comparison of ultrastructural changes and the anticarcinogenic effects of thymol and carvacrol on ovarian cancer cells: which is more effective?
(Taylor & Francis Inc, 2020)
Ovarian cancer is the seventh most common cancer worldwide in women. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isopropylphenol) ...
Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
(Springer, 2021)
Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In the present study, we aimed to investigate ...
The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia//reperfusion induced rats
(Comenius Univ, 2017)
OBJECTIVE: Our study aimed to investigate the possible modifying effects of leptin and combined use of resveratrol on rat renal I/R injury and their relationship on signal pathways and apoptosis-related mechanisms. BACKGROUND: ...
Effects of Humanin on Experimental Colitis Induced by 2,4,6-trinitrobenzene Sulphonic Acid in Rats
(Medknow Publications & Media Pvt Ltd, 2017)
Background/Aim: The excessive apoptosis of intestinal epithelial cells (IECs) partly accounts for the development of colonic inflammation and eventually results in ulcerative colitis (UC). Humanin, an endogenous anti-apoptotic ...
Anticancer effect of the fruit and seed extracts of Momordica charantia L. (Cucurbitaceae) on human cancer cell lines
(Pharmacotherapy Group, 2019)
Purpose: To investigate anticancer effects of Momordica charantia L. (M. charantia) fruit and seed extracts on some cancer cell lines. Methods: Human cancer cell lines, including lung cancer (A549), breast cancer (MCF-7), ...
THE EFFECTS OF SOME MINERALS ON APOPTOSIS AND DNA DAMAGE IN SODIUM FLUORIDE-ADMINISTERED RENAL AND OSTEOBLAST CELL LINES
(Int Soc Fluoride Research, 2019)
The present study was planned to investigate the effects of some minerals (MgCl2, Na2SeO3, AlCl3 CaCl2) on the expression and translocation of certain apoptotic markers in NaF-administered (at the rate of IC50) rat renal ...