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Investigation of genetic variations of IL17 for vitiligo disease
(Kuwait Medical Assoc, 2019)
Objective: Vitiligo is a disorder of pigmentation characterized by the presence of depigmented skin macules due to a chronic and progressive loss of melanocytes from the cutaneous epidermis. Among many different etiologic ...
Evaluation of the neuroprotective effects of ozone in an experimental spine injury model
(Amer Assoc Neurological Surgeons, 2020)
OBJECTIVE The pathophysiology of spine injury consists of primary and secondary damage mechanisms. The vast majority of treatments aim to prevent or at least stop the progression of secondary neurotoxic events during the ...
The effect of FOXO gene family variants and global DNA metylation on RRMS disease
(Elsevier, 2020)
Multiple sclerosis is a chronic disease that usually occurs with exacerbations and remissions in young adults, affects the central nervous system white matter in multiple localization, and is thought to be the result of ...
Microbiome and Longevity: High Abundance of Longevity-Linked Muribaculaceae in the Gut of the Long-Living RodentSpalax leucodon
(Mary Ann Liebert, Inc, 2020)
With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the ...
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
(Taylor & Francis Ltd, 2017)
Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ...
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)
Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ...
Protein Oxidation Levels After Different Corneal Collagen Cross-Linking Methods
(Lippincott Williams & Wilkins, 2016)
Purpose: To evaluate advanced oxidation protein products (AOPP) levels, superoxide dismutase (SOD) enzyme activity, and total sulfhydryl (TSH) levels in rabbit corneas after different corneal collagen cross-linking (CXL) ...
The relationship between hypertension and plasma allantoin, uric acid, xanthine oxidase activity and nitrite, and their predictive capacity in severe preeclampsia
(Taylor & Francis Inc, 2016)
It is controversial that uric acid (UA) levels are related to the severity of hypertension in preeclampsia (PE). Our aim in this study was to determine whether UA, xanthine oxidase activity (XOA), allantoin and nitrite ...
Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats
(Taylor & Francis Inc, 2016)
Antioxidants are potential therapeutic agents for reducing stress-induced organ damage. We investigated the effects of ascorbic acid and -carotene on oxidative stress-induced cerebral, cerebellar, cardiac and hepatic damage ...
Association between the pectoral muscles and rib anomalies in poland syndrome
(Wolters Kluwer Medknow Publications, 2020)
Introduction: The purpose of this study was to investigate the relationship between pectoralis major muscle (PMj) and rib defects in Poland syndrome (PS) and to evaluate the clinical findings and variabilities by the ...