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Toplam kayıt 97, listelenen: 51-60
Endotoxin exposure and puberty in female rats: the role of nitric oxide and caspase-1 inhibition in neonates
(Canadian Science Publishing, Nrc Research Press, 2015)
Bacterial toxins are widespread in the environment as well as in the digestive system of humans and animals. Toxin from Gram-negative bacteria (endotoxin or lipopolysaccharide; LPS) has a life-long programming effect on ...
Treatment with crocin suppresses diabetic nephropathy progression via modulating TGF-β1 and oxidative stress in an experimental model of pinealectomized diabetic rats
(Elsevier, 2022)
One of the most common complications of diabetes is diabetic nephropathy (DN). Uncontrolled hyperglycemia leads to histopathologic alterations in the kidney that prevent normal renal function. This study aimed to explore ...
cAMP/PKA-CREB-BDNF signaling pathway in hippocampus of rats subjected to chemically-induced phenylketonuria
(SPRINGER/PLENUM PUBLISHERS, 2021)
Phenylketonuria (PKU) is an inborn error disease in phenylalanine metabolism resulting from defects in the stages of converting phenylalanine to tyrosine. Although the pathophysiology of PKU is not elucidated yet, the toxic ...
Effect of Prefrontal Transcranial Direct Current Stimulation on Interoception in Healthy Individuals
(WILEY, 2022)
Interoception refers to the integration process of physiological signals arising from the internal body in the central nervous system.
Investigation of the Effect of Teripataid on Astrocytes
(WILEY, 2022)
Teriparatide is a form of parathyroid hormone which is an effective anabolic agent used in the treatment of osteoporosis
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia
(Springer, 2022)
Alzheimer's disease (AD) is by far the most common cause of cognitive impairment in older adults. Current treatments are entirely focused on the symptoms of AD. A complex etiology for AD has been proposed recently, in which ...
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
(Bentham Science, 2021)
Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells.
Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ...
Oxidative stress-induced apoptotic changes after acute exposure to antifouling agent zinc pyrithione (ZnPT) in Mytilus galloprovincialis Lamark (Mediterranean mussels) tissues
(TAYLOR & FRANCIS LTD, 2022)
Zinc pyrithione (ZnPT) is one of the components used in antifouling paints and can be an alternative to classical toxic chemicals such as organotin. However, there is still remarkable concern about the environmental safeness ...
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction
(Taylor and Francis Ltd., 2021)
The present study aimed to analyze the effects of pinealectomy and crocin treatment in isoproterenol-induced myocardial damage. Seventy rats were divided into seven groups: control, sham control, pinealectomy (PNX), ...
Melatonin is effective in attenuating cisplatin-induced neurotoxicity
(WILEY, 2022)
Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis ...