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Toplam kayıt 12, listelenen: 1-10
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
(Taylor & Francis Ltd, 2017)
Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ...
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)
Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ...
Effect of Sideritis leptoclada against HT-144 human malignant melanoma
(Lippincott Williams & Wilkins, 2018)
Sideritis leptoclada O. Schwarz et P.H. Davis extracts were evaluated for its singlet oxygen production capacity using spectrophotometric method. The extracts producing singlet oxygen were then evaluated for cytotoxicity ...
Protection by L-carnitine against radiation-induced ileal mucosal injury in the rat: Pattern of oxidative stress, apoptosis and cytokines
(Taylor & Francis Ltd, 2013)
Purpose : In this study, we tested the effects of L-carnitine (LC) on radiation-induced ileal mucosal damage. Materials and methods : Thirty Wistar albino rats were divided into five groups. The control group received ...
Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy
(Elsevier Ireland Ltd, 2016)
Objective: Diabetic neuropathy (DNP) is a frequent and serious complication of diabetes mellitus (DM) that leads to progressive and length-dependent loss of peripheral nerve axons. The purpose of the present study is to ...
Protective effects of quercetin against testis damage caused by cisplatin
(Taylor and Francis Ltd., 2021)
We investigated the effects of quercetin on cisplatin induced testicular toxicity using histopathological, immunohistochemical and biochemical methods. We used four groups of Wistar albino male: control, quercetin, cisplatin, ...
Preclinical study of the medicinal plants for the treatment of malignant melanoma
(Springer, 2020)
Melanoma is the most aggressive type of skin cancer and originates from pigment-containing cells called melanocytes. The incidence of melanoma has been increasing worldwide. In the current study, the cytotoxic and ...
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
(Academic Press, 2020)
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained enormous attention. The plausible reason and believe or mind set behind this fact is attributed to either lesser or no side effects ...
Application of talcum powder, trichloroacetic acid and silver nitrate in female rats for non-surgical sterilization: evaluation of the apoptotic pathway mRNA and miRNA genes
(Wiley, 2015)
There are several methods used for non-surgical sterilization in birth control including quinacrine, trichloroacetic acid (TCA), erythromycin, tetracycline, silver nitrate and talcum powder. Among these, talcum powder, TCA ...
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
(Bentham Science, 2021)
Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells.
Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ...