Ara
Toplam kayıt 18, listelenen: 11-18
Treatment with crocin suppresses diabetic nephropathy progression via modulating TGF-β1 and oxidative stress in an experimental model of pinealectomized diabetic rats
(Elsevier, 2022)
One of the most common complications of diabetes is diabetic nephropathy (DN). Uncontrolled hyperglycemia leads to histopathologic alterations in the kidney that prevent normal renal function. This study aimed to explore ...
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
(Korean Neurosurgical Society, 2021)
Objective: Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ...
An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
(Hindawi, 2021)
Purpose. The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. Methods. The study was conducted on twenty-four male rats. ...
Influence of Pinealectomy and Long-term Melatonin Administration on Inflammation and Oxidative Stress in Experimental Gouty Arthritis
(Springer, 2022)
Gout is an inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints or soft tissue. MSU crystals are potent inflammation inducers. Melatonin (MLT) is a powerful endogenous ...
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia
(Springer, 2022)
Alzheimer's disease (AD) is by far the most common cause of cognitive impairment in older adults. Current treatments are entirely focused on the symptoms of AD. A complex etiology for AD has been proposed recently, in which ...
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction
(Taylor and Francis Ltd., 2021)
The present study aimed to analyze the effects of pinealectomy and crocin treatment in isoproterenol-induced myocardial damage. Seventy rats were divided into seven groups: control, sham control, pinealectomy (PNX), ...
Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis
(TURKISH LEAGUE AGAINST RHEUMATISM, 2022)
Objectives: In this study, we aimed to investigate the differentiation potential of dental follicle mesenchymal stem cells (MSCs) in the synovial fluid (SF) niche of early-onset or end-stage rheumatoid arthritis (RA). ...
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
(Turkish Society of Cardiology, 2022)
Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ...