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Toplam kayıt 12, listelenen: 1-10
Anti-lung Cancer and Anti-angiogenic Activities of New Designed Boronated Phenylalanine Metal Complexes
(Bentham Science Publ Ltd, 2018)
Background: Drug design and discovery studies still remain of great importance in the search for more convenient chemotherapeutic to avoid the drug resistance, systemic toxicity or the long-term side effects. Objective: A ...
Evaluation of Multifunctional Hybrid Analogs for Stilbenes, Chalcones and Flavanones
(Bentham Science Publ Ltd, 2017)
Aims: In this study, discovery of novel anticancer agents acting by more than one mechanism was aimed. Method: For this purpose, eleven previously synthesized simple-stilbene, chalcone, flavanone derivatives and 31 novel ...
Design and synthesis of novel organometallic complexes using boronated phenylalanine derivatives as potential anticancer agents
(Taylor & Francis Ltd, 2019)
Drug design and discovery studies are important because of the prevalence of diseases without available medical cures. New anticancer agents are particularly urgent because of the high mortality rate associated with cancer. ...
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
(Academic Press, 2020)
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained enormous attention. The plausible reason and believe or mind set behind this fact is attributed to either lesser or no side effects ...
Organotin (IV) complexes derived from Schiff base 1,3-bis[(1E)-1-(2-hydroxyphenyl)ethylidene] thiourea: synthesis, spectral investigation and biological study to molecular docking
(Springer, 2021)
A novel Schiff base-derived organotin (IV) complexes have been synthesized by reacting 1, 3-bis [(1E)-1-(2-hydroxyphenyl)
ethylidene]thiourea (which in turn obtained by condensing thiourea with ortho-hydroxyacetophenone) ...
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential
(Bentham Science Publishers, 2021)
The overwhelming globalburden of cancer has posed numerous challenges and opportunities for developing anti-cancer therapies. Phytochemicalshave emerged as promising synergistic compounds with potential anti-cancer effects ...
Antimicrobial screening to molecular docking of newly synthesized ferrocenyl-substituted pyrazole
(QASSIM UNIV, 2022)
Objective: Microbial diseases are snowballing at an alarming proportion. Therefore, the intent of this study was to inspect the antimicrobial action of ferrocenyl-substituted pyrazole against various human pathogenic ...
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)
Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ...
Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions
(MDPI, 2022)
Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties, such as antioxidant, antidiabetic, ...
Gut Microbiota-Assisted Synthesis, Cellular Interactions and Synergistic Perspectives of Equol as a Potent Anticancer Isoflavone
(MDPI, 2022)
It is well known that, historically, plants have been an important resource of anticancer agents, providing several clinically approved drugs. Numerous preclinical studies have shown a strong anticancer potential of ...