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Toplam kayıt 9, listelenen: 1-9
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
(Elsevier, 2021)
Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ...
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)
Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ...
Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance
(Academic Press, 2020)
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained enormous attention. The plausible reason and believe or mind set behind this fact is attributed to either lesser or no side effects ...
NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target
(Elsevier, 2021)
Notch signaling, an evolutionarily conserved signaling cascade, is critical for normal biological processes of cell differentiation, development, and homeostasis. Deregulation of the Notch signaling pathway has been ...
Organotin (IV) complexes derived from Schiff base 1,3-bis[(1E)-1-(2-hydroxyphenyl)ethylidene] thiourea: synthesis, spectral investigation and biological study to molecular docking
(Springer, 2021)
A novel Schiff base-derived organotin (IV) complexes have been synthesized by reacting 1, 3-bis [(1E)-1-(2-hydroxyphenyl)
ethylidene]thiourea (which in turn obtained by condensing thiourea with ortho-hydroxyacetophenone) ...
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
(SPRINGER HEIDELBERG, 2022)
Nanotechnology has encouraged new and amended materials (metal nanoparticles) for therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) are versatile nanoscale entities, widely used to ...
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)
As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...
Chemopreventive mechanisms of amentoflavone: recent trends and advancements
(Springer Science and Business Media Deutschland GmbH, 2023)
In parallel to the continuous rise of new cancer cases all over the world, the interest of scientific community in natural anticancer agents has steadily been increased. In the past decades, numerous phytochemicals have ...
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
(Springer Science and Business Media Deutschland GmbH, 2023)
Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ...