Kurum Yazarı "Çetin, Esin Sakallı" Tıp Fakültesi İçin Listeleme
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The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
Bayram, D.; Çetin, Esin Sakallı; Kara, Murat; Özgöçmen, M.; Candan, I. A. (Sage Publications Ltd, 2017)Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ... -
Case Report: Y Chromosome Microdeletion in an Infertile Patient with Mosaic Klinefelter Syndrome
Çetinkaya, Mehmet; Kaba, Mehmet; Çetin, Esin Sakallı; Candan, Şükrü (Kamla-Raj Enterprises, 2015)Among genetic factors which contribute about 10-15 percent of male infertility, the most common genetic causes of male infertility are Klinefelter's Syndrome (KS) and Y chromosome microdeletions respectively. Most of the ... -
Methotrexate-Induced Nephrotoxicity in Rats: Protective Effect of Mistletoe (Viscum album L.) Extract
Çetin, Esin Sakallı; Tetiker, Hasan; Çelik, Özgür İlhan; Yılmaz, Nigar; Ciğerci, İbrahim Hakkı (Karger, 2017)Background: The protective effect of mistletoe extract (Helixor((R)), HLX) against methotrexate (MTX)-induced acute oxidative stress and nephrotoxicity in rats was evaluated by histological and biochemical methods as well ... -
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
Çetin, Esin Sakallı; Nazıroğlu, Mustafa; Çiğ, Bilal; Övey, İshak Suat; Koşar, Pınar Aslan (Taylor & Francis Ltd, 2017)Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ... -
Upregulation of SIRT1 gene in gastric adenocarcinoma
Özcan, Önder; Belli, Ahmet Korkut; Çetin, Esin Sakallı; Kara, Murat; Çelik, Özgur İlhan; Kaplan, Mehmet; Polat, Murat (Aves, 2019)Background/Aims: SIRT1 gene overexpression is reportedly associated with cancer development, via the triggering of DNA repair impairment, and cell proliferation. The study aimed to investigate SIRT1 expression in patients ...