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Toplam kayıt 14, listelenen: 1-10
Lack of association between increased mitochondrial DNA(4977) deletion and ATP levels of sputum cells from chronic obstructive pulmonary disease patients versus healthy smokers
(Taylor & Francis Ltd, 2017)
In this study we looked at smokers with and without chronic obstructive pulmonary disease (COPD) patients in order to evaluate the incidence of 4977 base pair (bp) mtDNA (mtDNA(4977)) deletion and mtDNA copy number in ...
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)
Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ...
IGF2BP2 gene polymorphism in patients with morbid obesity
(Allied Acad, 2017)
Background/Aim: In this study, it was aimed to determine the relationship between morbid obesity and insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs1470579 and rs4402960 gene polymorphisms. Materials and ...
MTUS1 tumor suppressor and its miRNA regulators in breast cancer
(Elsevier Science Bv, 2016)
Breast cancer is major public health problem predominantly effects female population. Current therapeutic approaches to deal with breast cancer are still lack of effectiveness. Thus, identifying/developing novel strategies ...
THE METHYLATION STATUS OF NKCC1 AND KCC2 IN THE PATIENTS WITH REFRACTORY TEMPORAL LOBE EPILEPSY
(Literatura Medica, 2019)
Purpose - Methylation is a key epigenetic modification of DNA and regarding its impact on epilepsy, it is argued that "DNA methylation may play an important role in seizure susceptibility and maintenance of the disorder". ...
The relationship between gestational diabetes mellitus and selenoprotein-P plasma 1 (SEPP1) gene polymorphisms
(Taylor & Francis Ltd, 2018)
Our aim is to demonstrate any correlation between gestational diabetes mellitus (GDM) and polymorphism of the selenoprotein P (SEPP1) gene encoding the SEPP1 protein, having a role in the insulin resistance in GDM. Forty ...
Endothelin-1 Lys198Asn and rs10478694 polymorphism in ischemic stroke.
(Scientific Publishers India, 2017)
Objective: In this study, we aimed to investigate the relationship between ischemic cerebrovascular diseases and Lys198Asn and rs10478694 polymorphism of Endothelin-1 gene, a strong vasoconstrictor. Materials and Methods: ...
IGF2BP2 gene polymorphism in patients with psoriasis.
(Allied Acad, 2017)
Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ...
IGF2BP2 gene polymorphism in patients with psoriasis
(Scientific Publishers of India, 2017)
Psoriasis is a chronic inflammatory disease with genetic transmission, the etiology of which has not been completely clarified yet. Insulin-like Growth Factor Binding Protein 2 (IGF2BP2) plays a role in growth, development, ...
Evaluation of RELN gene polymorphism in children with autism spectrum disorder
(Cumhuriyet Univ Tip Fak Psikiyatri Anabilim Dali, 2018)
Objective: With increasing frequency of autism spectrum disorder (ASD) in recent years, etiology has not yet been fully elucidated. Multiple hypotheses have been proposed to explain autism etiology including genetic, ...