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Toplam kayıt 11, listelenen: 1-10
Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis
(Elsevier Sci Ltd, 2020)
Background Study-level meta-analyses provide high-certainty evidence that heparin reduces the risk of symptomatic venous thromboembolism for patients with cancer; however, whether the benefits and harms associated with ...
Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements
(Sage Publications Ltd, 2020)
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer ...
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
(Elsevier, 2021)
Oncogenic transformation has been the major cause of global mortality since decades. Despite established therapeutic regimes, majority of cancer patients either present with tumor relapse, refractory disease or therapeutic ...
Deguelin targets multiple oncogenic signaling pathways to combat human malignancies
(Elsevier, 2021)
Cancer is an anomalous growth and differentiation of cells known to be governed by oncogenic factors. Plant-based natural metabolites have been well recognized to possess chemopreventive properties. Deguelin, a natural ...
Nodal tumor volume as a prognostic factor for head and neck squamous cell carcinoma: a systematic review
(FRONTIERS IN BIOSCIENCE INC, 2021)
Introduction: Several studies suggest that there is an association between the metastatic nodal tumor volume and the clinical outcome in patients with solid cancers. However, despite the prognostic potential of nodal volume, ...
NOTCH signaling: Journey of an evolutionarily conserved pathway in driving tumor progression and its modulation as a therapeutic target
(Elsevier, 2021)
Notch signaling, an evolutionarily conserved signaling cascade, is critical for normal biological processes of cell differentiation, development, and homeostasis. Deregulation of the Notch signaling pathway has been ...
Bioaccumulation and health risk assessment of heavy metals in European eels taken from Lakes Köyceğiz (Turkey) and Võrtsjärv (Estonia)
(Springer Science and Business Media Deutschland GmbH, 2021)
Monitoring heavy metal contaminants in fish is important for the assessment of environmental quality as well as food safety. In this study, European eel samples were collected from Lake Köyceğiz and Lake Võrtsjärv in 2017 ...
Cellular targets and molecular activity mechanisms of bee venom in cancer: recent trends and developments
(TAYLOR & FRANCIS INC, 2022)
Bee venom therapy is known as a traditional approach to curing many medical conditions such as arthritis, pain and rheumatism. Bee venom also provides promising potential for treating many cancers such as breast, lung, ...
Metal nanoparticles in cancer: from synthesis and metabolism to cellular interactions
(SPRINGER HEIDELBERG, 2022)
Nanotechnology has encouraged new and amended materials (metal nanoparticles) for therapeutic applications with specific prominence in healthcare. Metal nanoparticles (NPs) are versatile nanoscale entities, widely used to ...
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
(SPRINGER, 2022)
As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ...