Ara
Toplam kayıt 9, listelenen: 1-9
Molecular dynamics analysis of N-acetyl-D-glucosamine against specific SARS-CoV-2’s pathogenicity factors
(Public Library of Science, 2021)
The causative agent of the pandemic identified as SARS-CoV-2 leads to a severe respiratory illness similar to SARS and MERS with fever, cough, and shortness of breath symptoms and severe cases that can often be fatal. In ...
The effect of a seed coating with Origanum vulgare essential oil on Clavibacter michiganensis subsp. michiganensis
(Czech Academy of Agricultural Sciences, 2021)
The study aimed to evaluate the efficacy of a seed film coating with Origanum vulgare Linnaeus essential oil (EO) against Clavibacter michiganensis subsp. michiganensis (Cmm) on tomatoes. Tomato seeds (cv. Rio Grande) ...
Organotin (IV) complexes derived from Schiff base 1,3-bis[(1E)-1-(2-hydroxyphenyl)ethylidene] thiourea: synthesis, spectral investigation and biological study to molecular docking
(Springer, 2021)
A novel Schiff base-derived organotin (IV) complexes have been synthesized by reacting 1, 3-bis [(1E)-1-(2-hydroxyphenyl)
ethylidene]thiourea (which in turn obtained by condensing thiourea with ortho-hydroxyacetophenone) ...
Investigating anticancer potency of in vitro propagated endemic Thymus cilicicus Boiss. & Bal. extract on human lung, breast, and prostate cancer cell lines
(Springer Science and Business Media Deutschland GmbH, 2022)
Cancer is the leading cause of death in the world, accounting for nearly 10 million deaths in 2020 alone and surpassing all other categories by a large margin. Several different strategies have been and are still being ...
Antimicrobial screening to molecular docking of newly synthesized ferrocenyl-substituted pyrazole
(QASSIM UNIV, 2022)
Objective: Microbial diseases are snowballing at an alarming proportion. Therefore, the intent of this study was to inspect the antimicrobial action of ferrocenyl-substituted pyrazole against various human pathogenic ...
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
(MDPI, 2022)
Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ...
Synthesis, Crystal Structure, Hirshfeld Surface Analysis, DNA/BSA Interaction and Molecular Docking Studies of 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline
(Elsevier B.V., 2023)
We reported herein a new 1,2,4-triazine derivative, 2-(6-(4-chlorophenyl)-1,2,4-triazin-3-yl)quinoline, synthesized by cyclization of p‑chloro isonitrosophenylhydrazine with 2-quinolinecarboxaldehyde. Its structure was ...
Design, in Silico Studies and Biological Evaluation of New Chiral Thiourea and 1,3-Thiazolidine-4,5-dione Derivatives
(John Wiley and Sons Inc, 2023)
In this study, new chiral thiourea and 1,3-thiazolidine-4,5-dione derivatives were synthesized, it was aimed to evaluate the various biological activities and molecular docking of these compounds. Firstly, the new thioureas ...
Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
(nstitute for Ionics, 2023)
HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ...