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Toplam kayıt 33, listelenen: 1-10
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
(Taylor & Francis Ltd, 2017)
Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ...
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)
Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ...
3-Pyridinylboronic acid normalizes the effects of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in zebrafish embryos
(Taylor & Francis Ltd, 2020)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that damages dopaminergic neurons. Zebrafish has been shown to be a suitable model organism to investigate the molecular pathways in the pathogenesis of ...
ANTIFUNGAL ACTIVITY OF CURCUMIN CASPOFUNGIN COMBINATION AGAINST CANDIDA SPP. VIA APOPTOTIC INDUCTION
(Parlar Scientific Publications (P S P), 2018)
Phytochemicals with drug combinations have led to the discovery of different therapeutics used in fighting off the different types of infections. In this study, I have investigated the synergetic antifungal effect of ...
Effect of Sideritis leptoclada against HT-144 human malignant melanoma
(Lippincott Williams & Wilkins, 2018)
Sideritis leptoclada O. Schwarz et P.H. Davis extracts were evaluated for its singlet oxygen production capacity using spectrophotometric method. The extracts producing singlet oxygen were then evaluated for cytotoxicity ...
Parietin as an efficient and promising anti-angiogenic and apoptotic small-molecule from Xanthoria parietina
(Soc Brasileira Farmacognosia, 2019)
Lichens that are exclusive symbiotic organisms composed of fungus and alga, are considered as a wealthy source of biologically and pharmacologically active small-molecules thanks to the tight metabolic relationship between ...
The anticancer activity of visnagin, isolated from Ammi visnaga L., against the human malignant melanoma cell lines, HT 144
(Springer, 2019)
Melanoma is a cancer of melanocyte cells and has the highest global incidence. There is a need to develop new drugs for the treatment of this deadly cancer, which is resistant to currently used treatment modalities. We ...
Evaluation of serum M30 and M65 activity in patients with stage-I endometrial cancer
(Taylor & Francis Inc, 2019)
We aimed to analyse the prognostic value of serum oxidative stress parameters and apoptotic markers of serum M30/65 levels in endometrial cancer patients. Serum M30/65 levels and oxidative stress parameters were evaluated ...
Comparison of ultrastructural changes and the anticarcinogenic effects of thymol and carvacrol on ovarian cancer cells: which is more effective?
(Taylor & Francis Inc, 2020)
Ovarian cancer is the seventh most common cancer worldwide in women. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isopropylphenol) ...
Evaluation of cytotoxic, apoptotic effects and phenolic compounds of sea cucumber Holothuria tubulosa (Gmelin, 1791) extracts
(Scientific Technical Research Council Turkey-Tubitak, 2020)
This study aimed to investigate the potential cytotoxic effects and phenolic contents of aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Mugla (Turkey) against different cancer cells for ...