Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 193, listelenen: 113-132
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INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
(Süleyman Demirel Üniversitesi, 2022)Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ... -
Investigation on flow and heat transfer of compact brazed plate heat exchanger with lung pattern
(Pergamon-Elsevier Science Ltd, 2020)This study relates to an evaluation of the thermo-hydraulic performance for a state-of-the-art compact brazer plate heat exchanger (PHE) in 3 kW for 3-plates. To improve heat transfer and pressure drop of the PHE, a lung ... -
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ... -
İnsan Endometriyum Epitel Hücrelerinde Farklı Kontrollü Ovaryan Hipersitümulasyonu Protokollerinin Eksozom Belirteci CD63 Üzerine Etkisi
(Celal Bayar Üniversitesi, 2022)Giriş ve Amaç: Eksozomlar; protein, mRNA ve miRNA’ları taşıyan ve hedefledikleri hücrelerde/dokularda fonksiyonel değişikliklere neden olan kargo sistemleridir. CD63, eksozomların tanımlanması ve izolasyonu için anahtar ... -
Kanser Tanısı Alan Çocuk/Ergenlerin Onay Sürecine ve Tedaviye Katılımlarının Değerlendirilmesi
(2016)Kanser gibi yaşamı tehdit eden hastalık durumunda hekimler arasında tıbbi gerçeğin hastaya söylenmesi eğilimi her ülkenin kendi ahlaksal, sosyal ve kültürel yapısına göre farklılık gösterebildiği gibi, ülkelerin sağlık ... -
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
(Journal of Chemical Neuroanatomy, 2023)Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ... -
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
(Turkish Society of Cardiology, 2022)Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ... -
Linalool exhibits therapeutic and protective effects in a rat model of doxorubicin-induced kidney injury by modulating oxidative stress
(Taylor and Francis Ltd., 2021)The aim of the present study was to investigate the therapeutic and protective effects of linalool against doxorubicin (DOX)-induced kidney injury. Forty-eight Wistar rats were divided into 8 groups as follows; Control, ... -
Long-Term Prophylactic Transcranial Direct Current Stimulation Ameliorates Allodynia and Improves Clinical Outcomes in Individuals With Migraine
(ELSEVIER, 2023)Objectives: Migraine is a common and substantially debilitating disorder that may associate with allodynia, a marker of central sensitization in the pain circuits. Several unmet needs, like limited adherence to drugs due ... -
Losartan ameliorates ovarian ischaemia/reperfusion injury in rats: an experimental study
(Taylor & Francis Inc, 2020)This study aimed to investigate the protective and antioxidant role of losartan in ovarian ischaemia and ischaemia/reperfusion injury in an experimental ovarian torsion model. Thirty adult female rats were used. Rats were ... -
m 6 A Pathway Regulators Are Frequently Mutated in Breast Invasive Carcinoma and May Play an Important Role in Disease Pathogenesis
(Mary Ann Liebert, 2021)Breast invasive carcinoma (BIC) is one of the most commonly observed and the deadliest cancer among women. Studies examining the role of epigenetics and regulation of gene expression stand to make important strides in ... -
Melatonin is effective in attenuating cisplatin-induced neurotoxicity
(WILEY, 2022)Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis ... -
Methotrexate-Induced Nephrotoxicity in Rats: Protective Effect of Mistletoe (Viscum album L.) Extract
(Karger, 2017)Background: The protective effect of mistletoe extract (Helixor((R)), HLX) against methotrexate (MTX)-induced acute oxidative stress and nephrotoxicity in rats was evaluated by histological and biochemical methods as well ... -
Microbiome and Longevity: High Abundance of Longevity-Linked Muribaculaceae in the Gut of the Long-Living RodentSpalax leucodon
(Mary Ann Liebert, Inc, 2020)With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the ... -
miR-181a-5p is a potential candidate epigenetic biomarker in multiple sclerosis
(NLM (Medline), 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
miR-181a-5p is a potential candidate epigenetic biomarker in sclerosis
(CANADIAN SCIENCE PUBLISHING, 2022)Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) characterized by demyelination and axonal degeneration. Abnormal expression of microRNAs (miRNAs) plays an important role in MS ... -
Mistletoe (Viscum album L.) extract attenuates ıtraconazole-ınduced acute oxidative stress and hepatocellular ınjury in rats
(UNIV KARACHI, 2023)In the current study, the protective effect of a mistletoe extract (Helixor (R), HLX) on Itraconazole (ITZ)-induced hepatocellular injury and acute oxidative stress in rats was aimed to be investigated by histological, ... -
Mixed lineage kinase domain-like pseudokinase: Conventional (necroptosis) and unconventional (necroptosis-independent) functions and features
(Academic Press Inc., 2022)Mixed lineage kinase domain-like pseudokinase (MLKL) is the terminal and indispensable mediator of necroptosis. Necroptosis, also known as programmed cell necrosis, is a caspase-independent cell death mechanism involved ... -
Morphometric assessment of important landmarks on skull intended for Vidian nerve surgery
(Springer, 2020)Purpose: The aim of our study was to determine guide parameters for clinicians by morphometric assessment of important landmarks on cranium intended for Vidian nerve surgery. Methods: For the study, 23 half-skull bases, ... -
MRI-based detailed evaluation of the anatomy of the human coccyx among Turkish adults
(Medknow Publications & Media Pvt Ltd, 2017)Aim: The human coccyx varies considerably in shape and size. The objective of this study was to investigate the morphology and morphometry of the coccyx on pelvic magnetic resonance imaging in asymptomatic individuals among ...