Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 193, listelenen: 8-27
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Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease
(PMC, 2022)Acetylcholinesterase and butyrylcholinesterase (AChE and BChE) are involved in modulating cholinergic signaling, but their roles in Alzheimer's and Parkinson's diseases (AD and PD) remain unclear. We identified a higher ... -
Aminoguanidine mitigates apoptosis, testicular seminiferous tubules damage, and oxidative stress in streptozotocin-induced diabetic rats
(Churchill Livingstone, 2015)This study aimed to investigate the effect of aminoguanidine (AG) against testicular damage streptozotocin (STZ) induced diabetes. Thirty two rats were separated into four groups: control, AG, STZ and STZ + AG. In the STZ ... -
Anatomical variation in the origin of left vertebral artery: A case report
(Ege Üniversitesi, 2020)We report an abnormal origin of a vertebral artery (VA) on the left side of a 72-year-old male cadaver and refer to its clinical importance. In this cadaver, the left VA was originated from a common trunk with the left ... -
Anatomy and variations of plantaris muscle in fetuses
(Anatomical Soc India, 2015)Introduction: We have aimed at researching into the morphometric development and variations of the plantaris muscle and its tendon throughout the fetal period and comparing them with the results of the study performed on ... -
Anti-Inflammatory and Anti-Fibrotic Effects of Ursodeoxycholic Acid in Streptozocin-Induced Diabetic Rats
(Kocaeli Derince Eğitim ve Araştırma Hastanesi, 2020)INTRODUCTION: Diabetic cardiomyopathy is a consequence of free fatty acid oxidation, dysfunction in mitochondria, oxidative stress and diffuse myocardial fibrosis. We aimed to investigate the anti-inflammatory and anti-fibrotic ... -
Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells
(TAYLOR & FRANCIS INC, 2022)Breast cancer is the most common cancer in women in the world. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Linalool is aromatic compounds from ... -
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
(Elsevier Ltd, 2023)Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR ... -
Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
(Springer, 2021)Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In the present study, we aimed to investigate ... -
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ... -
Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats
(Taylor & Francis Inc, 2016)Antioxidants are potential therapeutic agents for reducing stress-induced organ damage. We investigated the effects of ascorbic acid and -carotene on oxidative stress-induced cerebral, cerebellar, cardiac and hepatic damage ... -
Assessment of acute aerobic exercise in the morning versus evening on asprosin, spexin, lipocalin-2, and insulin level in overweight/obese versus normal weight adult men
(Taylor & Francis Inc, 2020)The aim of this study was to examine the acute effect of aerobic exercise when performed in the morning and evening on obesity-related hormones of asprosin, spexin, lipocalin-2, and insulin in normal weight (NW) and ... -
Assessment of biological rhythm disturbances and emotion recognition in individuals with or without obstructive sleep apnea syndrome: The role of eating patterns
(Taylor and Francis Ltd., 2023)Although a vast amount of research efforts including a plethora of distinct methodologies have been put forth, the pathophysiology of obstructive sleep apnea syndrome (OSAS) has not been compromised and multidimensional ... -
Assessment of COL1A1 and MMP9 expression in patients with dermatochalasis
(Springer, 2020)Purpose Dermatochalasis is a clinical condition characterized by loss of elasticity of eyelid skin and soft tissue, which typically affects the elderly population. The aim of this study is to investigate the mRNA expression ... -
Association between the anthropometric measurements and dietary habits on telomere shortening in healthy older adults: A-cross-sectional study
(John Wiley and Sons Inc, 2023)im: This study aimed to evaluate the effect of anthropometric measurements and dietary habits on telomere length in healthy older residents in rural and urban areas. Methods: This was a cross-sectional study. The study ... -
Association between the pectoral muscles and rib anomalies in poland syndrome
(Wolters Kluwer Medknow Publications, 2020)Introduction: The purpose of this study was to investigate the relationship between pectoralis major muscle (PMj) and rib defects in Poland syndrome (PS) and to evaluate the clinical findings and variabilities by the ... -
Association of Adult Attention Deficit Hyperactivity Disorder With Dopamine Transporter Gene, Dopamine D3 Receptor, and Dopamine D4 Receptor Gene Polymorphisms
(Kure Iletisim Grubu A S, 2010)Objective: Attention deficit hyperactivity disorder (ADHD) is a developmental disorder which is characterized by inattention, impulsiveness, and hyperactivity. The etiology of ADHD is not completely understood, but it is ... -
Association of SNAP-25 Gene Ddel and Mnll Polymorphisms with Adult Attention Deficit Hyperactivity Disorder
(Korean Neuropsychiatric Assoc, 2014)Objective The synaptosomal-associated protein of 25 kDa (SNAP-25) gene is a presynaptic plasma membrane protein and an integral component of the vesicle docking and fusion machinery mediating secretion of neurotransmitters. ... -
Association of Synapsin III Gene with Adult Attention Deficit Hyperactivity Disorder
(Mary Ann Liebert, Inc, 2013)It was aimed to investigate the association of the synapsin III gene -196 G> A and -631 C>G polymorphisms that takes place in an encoding presynaptic protein, with adult attention deficit hyperactivity disorder (ADHD). One ... -
Attitudes towards and experiences of ethical dilemmas in treatment decision-making process among medical oncologists
(Wiley, 2020)Aim: This study aimed to evaluate the attitudes towards and experiences of ethical dilemmas in the treatment decision-making process among medical oncologists who are the members of the Turkish Society of Medical Oncology. ... -
Axolotl: A resourceful vertebrate model for regeneration and beyond
(WILEY, 2022)The regenerative capacity varies significantly among the animal kingdom. Successful regeneration program in some animals results in the functional restoration of tissues and lost structures. Among the highly regenerative ...
