Başlık için Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 193, listelenen: 133-152
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The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy
(Taylor and Francis Ltd., 2021)Diabetic neuropathy (DN) is the most common degenerative complication associated with Diabetes Mellitus. Despite widespread awareness about DN, the only effective treatments are blood glucose control and pain management. ... -
Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats
(Elsevier B.V., 2022)The current study aimed to evaluate the neuroprotective effect of exogenous melatonin against acrylamide (ACR)-induced oxidative stress and inflammatory and apoptotic responses in the brain tissues in pinealectomized rats ... -
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
(TAYLOR & FRANCIS INC, 2021)Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ... -
A new strategy to achieve high antimicrobial activity: green synthesised silver nanoparticle formulations with Galium aparine and Helichrysum arenarium
(SCIENDO, 2023)Silver nanoparticles (AgNPs), which have recently gained attention due to their antimicrobial activity, can also be produced by green synthesis. The aims of this study were to (i) characterise green synthesized AgNPs using ... -
Novel activity of human BChE: Lipid hydrolysis
(ELSEVIER FRANCE, 2023)Acetylcholinesterase and butyrylcholinesterase (BChE) typically hydrolyze the neurotransmitter acetylcholine. The multifunctional enzyme BChE is associated with lipid metabolism through an undefined mechanism. Based on ... -
Novel Fructose-1,6-bisphosphatase Gene Mutation in Two Siblings
(Mary Ann Liebert, Inc, 2013)Fructose-1,6-bisphosphatase (FBPase) deficiency is an autosomal, recessively inherited disease that progresses with severe hypoglycemia, and metabolic attacks result in a defect in gluconeogenesis. If not appropriately ... -
Obesity and the Mother Goddess of Neolithic Çatalhöyük
(Springer Science and Business Media Deutschland GmbH, 2023)Letter to Editor -
Oxidative stress-induced apoptotic changes after acute exposure to antifouling agent zinc pyrithione (ZnPT) in Mytilus galloprovincialis Lamark (Mediterranean mussels) tissues
(TAYLOR & FRANCIS LTD, 2022)Zinc pyrithione (ZnPT) is one of the components used in antifouling paints and can be an alternative to classical toxic chemicals such as organotin. However, there is still remarkable concern about the environmental safeness ... -
Oxytocin and cabergoline alleviate ovarian hyperstimulation syndrome (OHSS) by suppressing vascular endothelial growth factor (VEGF) in an experimental model
(Springer Heidelberg, 2020)Purpose Ovarian hyperstimulation syndrome (OHSS) is a life-threatening complication of ovarian stimulation in reproductive medicine. Here, we aimed to investigate the role of oxytocin (OT) and cabergoline in the prevention ... -
Patient's companions as a vulnerable group in Turkish hospitals: A descriptive study
(Blackwell Publishing Ltd, 2020)Background: In Turkish hospitals, in addition to health care professionals, there are people who are also a significant part of the health care services; even though they are not professionals. In Turkey, these people are ... -
Physiological parameters as a tool in the diagnosis of fibromyalgia syndrome in females: A preliminary study
(Pergamon-Elsevier Science Ltd, 2016)Aims: Although fibromyalgia (FM) syndrome is associated with many symptoms, there is as yet no specific finding or laboratory test diagnostic of this syndrome. The physical examination and laboratory tests may be helpful ... -
Phytochemistry, Biological Activity and Toxicity of Botanical Dietary Supplement: KL21
(Celal Bayar Üniversitesi, 2022)The use of nutritional supplements has grown conspicuously over the last decades. The present study aimed to design, develop, and optimize the toxicological and biological procedures to perform the quantitative determination ... -
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by alpha-naphthylthiourea
(TAYLOR & FRANCIS LTD, 2022)We aimed to observe the possible effects of melatonin (MLT) deprivation (pinealectomy) and exogenous MLT administration on pulmonary edema induced by alpha-naphthylthiourea (ANTU), a toxic chemical agent, in rats. Seventy ... -
Platelet-Rich Plasma in Vitrification; is it Helpful or Harmful?
(University of Agriculture, 2023)Human and animal studies on cryoprotectants and freezing solutions are still needed to establish a simple yet reliable protocol and increase the success of cryopreservation. The main aim of this study was to evaluate the ... -
Pneumatization of crista galli in Pre-adult and Adult Stages
(Soc Chilena Anatomia, 2016)The sinonasal region in humans is one of the regions that commonly shows anatomical variations. These variations can be easily diagnosed by paranasal CT evaluation. One of these variations is Crista galli pneumatization. ... -
Possibility of Taking an Offensive Stance in Extravasation Injury: Effects of Fat Injection in Vesicant (Doxorubicin) Induced Skin Necrosis Model in Rats
(Taylor and Francis Ltd., 2021)Introduction: Extravasation injuries are one of the most feared complications of intravenous drug administration. The most common drugs associated with extravasation injury include chemotherapy agents and contrast media. ... -
A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells
(Springer Science and Business Media B.V., 2023)Background: Despite recent advances in drug discovery, cancer is still one of the most lethal health problems worldwide. In most cases, standard therapy methods and multi-modal treatments fail, and new therapeutic approaches ... -
The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat
(Taylor & Francis Ltd, 2020)Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ... -
Preclinical Molecular Signatures of Spinal Cord Functional Restoration: Optimizing the Metamorphic Axolotl (Ambystoma mexicanum) Model in Regenerative Medicine
(Mary Ann Liebert, Inc, 2020)Regenerative medicine offers hope for patients with diseases of the central and peripheral nervous system. Urodele amphibians such as axolotl display an exceptional regenerative capacity and are considered as essential ... -
Prodynorphin (PDYN) gene polymorphisms in Turkish patients with methamphetamine use disorder, changes in PDYN serum levels in withdrawal and the relationship between PDYN, temperament and depression
(Routledge Journals, Taylor & Francis Ltd, 2020)Aim of the study is to compare prodynorphin (PDYN) rs1997794, rs1022563, rs6045819, rs2235749 polymorphisms in individuals with methamphetamine use disorder (MD) to that of healthy controls (HC), and to investigate the ...