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Toplam kayıt 97, listelenen: 91-97
Survival outcomes of hypomethylating agents maintenance therapy in new diagnosed AML patients: Real experience data
(PMC, 2022)
Objective: Acute myeloid leukemia (AML) is a hematological malignancy that frequently affects elderly population. With introducing the hypomethylating agents (HMAs) in elderly AML treatment, survival rates and quality of ...
Assessment of biological rhythm disturbances and emotion recognition in individuals with or without obstructive sleep apnea syndrome: The role of eating patterns
(Taylor and Francis Ltd., 2023)
Although a vast amount of research efforts including a plethora of distinct methodologies have been put forth, the pathophysiology of obstructive sleep apnea syndrome (OSAS) has not been compromised and multidimensional ...
The effects of PKI-402 on breast tumor models' radiosensitivity via dual inhibition of PI3K/mTOR
(INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2023)
PurposePI3K/Akt/mTOR pathway activation causes relapse and resistance after radiotherapy in breast cancer (BC). We aimed to radiosensitize BC cell lines to irradiation (IR) by PKI-402, a dual PI3K/mTOR inhibitor.MethodsWe ...
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
(Journal of Chemical Neuroanatomy, 2023)
Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ...
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
(Elsevier Ltd, 2023)
Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR ...
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
(Elsevier Ltd, 2023)
Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ...
Long-Term Prophylactic Transcranial Direct Current Stimulation Ameliorates Allodynia and Improves Clinical Outcomes in Individuals With Migraine
(ELSEVIER, 2023)
Objectives: Migraine is a common and substantially debilitating disorder that may associate with allodynia, a marker of central sensitization in the pain circuits. Several unmet needs, like limited adherence to drugs due ...