Kurum Yazarı "Genç, Deniz" PubMed İndeksli Yayınlar Koleksiyonu İçin Listeleme
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1,25-dihydroxyvitamin D3 regulates t helper and b lymphocyte responses substantially in drug-naive primary Sjogren's syndrome patients' mononuclear cells
Genç, Deniz; Sezer Kürkçü, Merve; Günaydın, Burcu; Tarhan, Emine Figen (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2021)Background/aim: A correlation between vitamin D deficiency and primary Sjogren's syndrome (pSS) has already been described. The limited data has been reported regarding the pathological relevance of vitamin D in primary ... -
Asthma immunotherapy and treatment approaches with mesenchymal stem cells
Akkoc, Tunc; Genç, Deniz (Future Medicine Ltd, 2020)Asthma is a chronic inflammatory disease of the airways where exaggerated T helper 2 immune responses and inflammatory mediators play a role. Current asthma treatment options can effectively suppress symptoms and control ... -
Dental follicle mesenchymal stem cells ameliorated glandular dysfunction in Sjögren's syndrome murine model
Genç, Deniz; Bulut, Osman; Günaydın, Burcu; Göksu, Mizgin; Düzgün, Mert; Dere, Yelda; Sezgin, Serhat; Aladağ, Akın; Bülbül, Aziz (Plos, 2022)Objective: Dental mesenchymal stem cells (MSCs) are potential for use in tissue regeneration in inflammatory diseases due to their rapid proliferating, multilineage differentiation, and strong anti-inflammatory features. ... -
Mesenchymal Stem Cells Combined With IFN gamma Induce Apoptosis of Breast Cancer Cells Partially Through TRAIL
Yenilmez, Ezgi Nurdan; Genç, Deniz; Farooqi, Ammad Ahmad; Tunoğlu, Servet; Zeybek, Ümit; Akkoç, Tunç; Yaylım, İlhan (Int Inst Anticancer Research, 2020)Background: Mesenchymal stem cells (MSCs) have gained remarkable attention because of their ability to dualistically regulate tumor growth. The main objective of this study was to evaluate the apoptotic effects of human ... -
Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis
Genç, Deniz; Sezer Kürkçü, Merve; Yiğittürk, Gürkan; Günaydın, Burcu; Elbe, Hülya; Aladağ, Akın; Çöl, Bekir; Tarhan, Emine Figen (TURKISH LEAGUE AGAINST RHEUMATISM, 2022)Objectives: In this study, we aimed to investigate the differentiation potential of dental follicle mesenchymal stem cells (MSCs) in the synovial fluid (SF) niche of early-onset or end-stage rheumatoid arthritis (RA). ... -
TNF-α, IL-1B and IL-6 affect the differentiation ability of dental pulp stem cells
Genç, Deniz; Sazak Öveçoğlu, Hesna; Akkoç, Tunç (PMC, 2023)Background: This in vitro study examined the effect of the inflammatory cytokines (tumour necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6) on osteogenic, chondrogenic, and adipogenic differentiation of dental pulp ...