Moleküler Biyoloji ve Genetik Bölümü Koleksiyonu: Recent submissions
Now showing items 1-20 of 125
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Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
(PMC, 2023)Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ... -
A new 1,2,4-triazine-n-oxide compound: Synthesis, crystal structure, Hirshfeld surface analysis and supercapacitor applications
(Elsevier B.V., 2023)In this paper, we report the one-step, metal catalyst-free synthesis of 6-(4-chlorophenyl)-3,3-dimethyl-4-(N-oxide)-1,2,3,4-tetrahydro-1,2,4-triazine using 2,4-dihydroxyacetophenone and p‑chloro isonitrosophenyl hydrazine ... -
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
(Springer Science and Business Media Deutschland GmbH, 2023)Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ... -
Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
(nstitute for Ionics, 2023)HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ... -
A new species of Saxifraga (Saxifragaceae) from northeastern Anatolia, Turkey
(Magnolia Press, 2023)Saxifraga kavrunensis, a new species endemic to Turkey, is described and illustrated. Samples from its natural population were collected from the Kaçkar Mountains in Rize Province. Although it has similar features to S. ... -
A potential posttranscriptional regulator for p60-katanin: miR-124-3p
(John Wiley and Sons Inc, 2023)Katanin is a microtubule severing protein belonging to the ATPase family and consists of two subunits; p60-katanin synthesized by the KATNA1 gene and p80-katanin synthesized by the KATNB1 gene. Microtubule severing is one ... -
Adjuvant composite cold atmospheric plasma therapy increases antitumoral effect of doxorubicin hydrochloride
(PMC, 2023)Introduction: Cancer is a global health concern, with a significant impact on mortality rates. Despite advancements in targeted antitumor drugs, the development of new therapies remains challenging due to high costs and ... -
Host-Induced Gene Silencing: Approaches in Plant Disease Management
(Springer International Publishing, 2023)Crops exposed to the damage of various biotic and abiotic sources result in reduced yields and cause economic losses. There are prominent strategies such as breeding for improved resistance, the application of pesticides, ... -
The effects of the Rheum ribes plant extract on inflammation, extracellular matrix remodeling, and obesity suggest a therapeutic potential
(Springer Science and Business Media B.V., 2023)Background: The prevalence of obesity is increasing in the world, and the Type II diabetes associated with obesity led researchers to seek alternative methods to treat these two chronic diseases. In the case of obesity and ... -
Genetic diversity of the cosmopolitan long-legged fly Syntormon pallipes in Turkey
(Taylor and Francis Ltd., 2023)Syntormon pallipes is one of the cosmopolitan species in the family Dolichopodidae. It has an important role in agriculture and forest ecosystems. We studied the genetic diversity of 10 populations of this species using ... -
Contributions to the Dolichopodidae (Insecta: Diptera) Fauna of Mu?la Provinces with the Six New Records for Turkey
(GAZI ENTOMOLOGICAL RESEARCH SOC, 2023)In this study, we report the Turkey fauna of long-legged flies and new records of six species (Diptera: Dolichopodidae) collected from Mugla province during the 2018-2019 field trips. These newly recorded species are ... -
CRYOPRESERVATION OF MENTHA PIPERITA L. GERMPLASM AND CONFIRMATION OF GENETIC STABILITY AFTER CRYO-STORAGE
(PAKISTAN AGRICULTURAL SCIENTISTS FORUM, 2023)Peppermint is an important aromatic-medicinal plant species and it has valuable essential oil contents such as menthol, linalool and limonene. The main purpose of the current study was to optimize a protocol for cryopreservation ... -
A New Cephalaria (Caprifoliaceae) Species from Turkey
(Magnolia Press, 2023)Cephalaria saldaensis, collected from Eşeler Mountain around Salda Lake (Yeşilova-Burdur), one of Turkey’s important tourism regions, is described from South-West Anatolia as a new species. Diagnostic morphological and ... -
Comparison of the effect of different glide path files on amount of apically extruded debris in curved root canals
(John Wiley and Sons Inc, 2023)It is essential to create a glide path before root canal preparation with nickel–titanium rotary files to avoid file breakage and preserve the original canal structure. The aim of this study was to compare the amount of ... -
Modification of multi-walled carbon nanotubes with platinum-osmium to develop stable catalysts for direct methanol fuel cells
(Royal Society of Chemistry, 2023)In the study, a new bimetallic catalyst was synthesized for methanol oxidation using multi-walled carbon nanotube (MWCNT)-supported platinum-osmium (PtOs) nanoparticles (PtOs@MWCNT NPs). The morphological structures of the ... -
Chemopreventive mechanisms of amentoflavone: recent trends and advancements
(Springer Science and Business Media Deutschland GmbH, 2023)In parallel to the continuous rise of new cancer cases all over the world, the interest of scientific community in natural anticancer agents has steadily been increased. In the past decades, numerous phytochemicals have ... -
BACTERIAL MICROBIOTA AND CHEMICAL PROPERTIES OF TURKISH TARHANA
(Slovak University of Agriculture, 2023)Tarhana is one of the traditional Turkish fermented food and it is served as a soup. In this study, bacterial microbiota and chemical properties (acidity, salt, and moisture content) of tarhana samples (n=96) were examined. ... -
A new hydrazone compound with ester groups: synthesis, spectroscopic studies, crystal structure, and electrochemical supercapacitor applications
(SPRINGER WIEN, 2022)We work and report the synthesis, spectroscopic results, and crystal structure of the title compound (H2L1), in this manuscript. The crystal structure of the title compound was determined using the X-ray diffraction method. ... -
Antioxidant, Cytotoxicity, Apoptotic Properties of Extracts of Andricus sternlichti galls and Their Phenolic Characterisation by HPLC
(John Wiley and Sons Inc, 2022)Quercus L. galls have been used in Western and Eastern cultures for various diseases in traditional medicine. Galls are also used in the East for many purposes, including consumption as food, commercial inks, leather ... -
Phloretin, as a Potent Anticancer Compound: From Chemistry to Cellular Interactions
(MDPI, 2022)Phloretin is a natural dihydrochalcone found in many fruits and vegetables, especially in apple tree leaves and the Manchurian apricots, exhibiting several therapeutic properties, such as antioxidant, antidiabetic, ...
