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dc.contributor.authorKaraogullarindan, Umit
dc.contributor.authorTarhan, Emine Figen
dc.contributor.authorOruk, Gonca
dc.date.accessioned2020-11-20T14:40:07Z
dc.date.available2020-11-20T14:40:07Z
dc.date.issued2020
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.urihttps://doi.org/10.17826/cumj.669775
dc.identifier.urihttps://hdl.handle.net/20.500.12809/666
dc.descriptionWOS: 000537976000009en_US
dc.description.abstractPurpose: In this study, the frequency of thyroid disorders in psoriatic arthritis (PsA) patients and the effect of anti TNF-alpha treatment on autoimmune thyroid disease were investigated. Materials and Methods: Thyroid stimulating hormone, triiodothyronine, thyroxine, antithyroglobulin(Tg) and anti-thyroid peroxidase (TPO) of 95 patients followed at the rheumatology outpatient clinic were retrospectively evaluated. Sixty-six patients with PsA (F/M: 43/23) whose data were complete, and 35 healthy controls (F/M: 25/10) were included in the study. Thyroid ultrasonography was applied to all cases by an endocrinology specialist. Results :38 of the PsA patients received disease modifying antirheumatic drugs (DMARDs) (Group 1; mean age: 43.94 +/- 9.81), and 28 anti TNF-alpha treatment (Group 2; mean age:42.25 +/- 11.48). Group 3 was comprised of healthy controls (mean age: 40.52 +/- 8.34). Significant differences were observed between the mean anti-TPO values and anti-Tg values of all groups. Conclusion: Autoimmune thyroid disorders were observed more frequently in patients with PsA than in the control group. The PsA patients who are receiving DMARDs appeared to have autoimmune thyroid disorders more frequently than those receiving anti TNF-alpha treatment. This condition may be resulting from TNF-alpha on the pathogenesis of thyroid disorders.en_US
dc.item-language.isoturen_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPsoriatic Arthritisen_US
dc.subjectAnti-TNFen_US
dc.subjectThyroid Dysfunctionen_US
dc.titleFrequency of autoimmune thyroid disorders in patients with psoriatic arthritis and effect of anti-TNF alpha treatmenten_US
dc.item-typearticleen_US
dc.contributor.departmenten_US
dc.contributor.departmentTemp[Karaogullarindan, Umit] Necip Fazil Sehir Hastanesi, Gastroenterol Bolumu, Kahramanmaras, Turkey -- [Tarhan, Emine Figen] Mugla Sitki Kocman Univ, Romatol Bilim Dali, Mugla, Turkey -- [Oruk, Gonca] Izmir Katip Celebi Univ, Endokrinol Bilim Dali, Izmir, Turkeyen_US
dc.identifier.doi10.17826/cumj.669775
dc.identifier.volume45en_US
dc.identifier.issue2en_US
dc.identifier.startpage461en_US
dc.identifier.endpage467en_US
dc.relation.journalCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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