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dc.contributor.authorKıvrak, Şeyda
dc.contributor.authorGöktürk, Tolga
dc.contributor.authorKıvrak, İbrahim
dc.date.accessioned2020-11-20T17:51:07Z
dc.date.available2020-11-20T17:51:07Z
dc.date.issued2017
dc.identifier.issn2148-6905
dc.identifier.issn2148-6905
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TWpVMU9UUTRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12809/8681
dc.description.abstractPhenolic compounds, which are secondary metabolites of plants, are one of the main groups of compounds that provide antiallergic, antiinflammatory, antimicrobial, antioxidant, cardioprotective properties of medicinal and aromatic plants. These broad physiological effects that they possess lead researchers to examine the phenolic contents of plants. Tilia tomentosa Moench is one of 45 species belonging to Tiliaceae family, and the use of flowers in traditional treatment methods is quite common. Although it is well known that T. tomentosa flowers are rich in phenolics with various biological functions, there is no recent study on determination of phenolic compounds of T. tomentosa flowers using UPLC-ESI-MS/MS. In this study, firstly, T. tomentosa flowers were extracted using hexane and volatile oil fractions were separated from the plant. Distilled water:methanol (50:50) mixture was added to the remaining flower part at 40 ° C and that subjected to extraction for 15 min. The obtained extract was filtered and dried in a lyophilizer at -70 ° C. The residue was redissolved in a mixture of distilled water:methanol (80:20). The sample was analyzed by UPLC-MS/MS (Waters Acquity Ultra Performance LC, Xevo TQ-S MS/MS) by passing through Macherey-Nagel Chromafil Xtra PTFE-20/25 0.20 ?m filters. According to the analysis results, 3,4-dihydroxybenzoic acid (66.820 mg/kg), myricetin (29.395 mg/kg), rutin (21.421 mg/kg), ferulic acid (12.334 mg/kg) and 3,4-dihydroxybenzaldehyde (10.383 mg/kg) were detected. T. tomentosa flowers have great potential to usage in industries such as food, medicine and cosmetic due to its rich content of phenolics.en_US
dc.item-language.isoengen_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiyolojien_US
dc.titleDetermination of Phenolic Composition of Tilia Tomentosa Flowers Using UPLC-ESI-MS/MSen_US
dc.item-typearticleen_US
dc.contributor.departmenten_US
dc.contributor.departmentTempDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Muğla Sıtkı Koçman University, Muğla, Turkey; Department of Chemistry and Chemical Treatment Technologies, Muğla Vocational School of Higher Education, Muğla Sıtkı Koçman University, Muğla, Turkey; Department of Chemistry and Chemical Treatment Technologies, Muğla Vocational School of Higher Education, Muğla Sıtkı Koçman University, Muğla, Turkeyen_US
dc.identifier.volume4en_US
dc.identifier.issue3en_US
dc.identifier.startpage249en_US
dc.identifier.endpage256en_US
dc.relation.journalInternational Journal of Secondary Metaboliteen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanen_US


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