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dc.contributor.authorSorucu, Ali
dc.contributor.authorOruç, Hasan Hüseyin
dc.date.accessioned2020-11-20T14:41:17Z
dc.date.available2020-11-20T14:41:17Z
dc.date.issued2019
dc.identifier.issn2193-4126
dc.identifier.issn2193-4134
dc.identifier.urihttps://doi.org/10.1007/s11694-019-00166-9
dc.identifier.urihttps://hdl.handle.net/20.500.12809/902
dc.description0000-0002-0496-9498en_US
dc.descriptionWOS: 000481420900085en_US
dc.description.abstractThe present study aimed to determine the effect of season and altitude to amount and prevalence of phenolic compounds in propolis. For the aim, 174 propolis samples were collected from 58 stationary apiaries from altitudes of 0-200 m, 200-500 m and above 500 m in spring, summer, and autumn distributed in the Marmara region of Turkey. Ethanol-extracted propolis samples were analyzed by LC-MS/MS to determine nine flavonoids and seven phenolic acids. Significant differences were found in average levels of galangin, naringenin, pinocembrin, quercetin, luteolin, caffeic acid, trans-cinnamic acid, p-coumaric acid, m-coumaric acid, and CAPE across the seasons and altitudes (P < 0.05). However, no differences were found levels of rutin, apigenin, kaempferol, ferulic acid and gallic acid (P < 0.05). Most of the significant differences were found between spring and autumn (10 differences). The prevalence of flavonoids was generally lower than phenolic acids. CAPE and pinocembrin had majority of the significant differences in phenolic compounds according to season and altitude. The prevalence of pinocembrin 100%, m-coumaric acid 99.4%, CAPE 99.4%, naringenin 99.4%, caffeic acid 98.9%, p-coumaric acid 98.3%, quercetin 96% and luteolin 95.4% were determined that dominant phenolic compound of Marmara Region of Turkey's propolis. Furthermore, Salix spp. 75.8%, Quercus spp. 74.4%, Populus spp. 72.4%, and Pinus spp. 53.5% were mainly determined source of propolis around the apiaries. These results show that different sampling of seasons and altitudes effect chemical composition of propolis even from the same area. The study indicated that seasons and altitudes are important factors for standardization of propolis.en_US
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [1120017]en_US
dc.description.sponsorshipThe project was supported by TUBITAK (1120017).en_US
dc.item-language.isoengen_US
dc.publisherSpringeren_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPropolisen_US
dc.subjectStandardizationen_US
dc.subjectPhenolic Compoundsen_US
dc.subjectSeasonen_US
dc.subjectAltitudeen_US
dc.subjectLC-MSen_US
dc.subjectMSen_US
dc.titleDetermination of biologically active phenolic compounds in propolis by LC-MS/MS according to seasons and altitudesen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Milas Veteriner Fakültesi, Klinik Öncesi Bilimler Bölümüen_US
dc.contributor.institutionauthorSorucu, Ali
dc.identifier.doi10.1007/s11694-019-00166-9
dc.identifier.volume13en_US
dc.identifier.issue3en_US
dc.identifier.startpage2461en_US
dc.identifier.endpage2469en_US
dc.relation.journalJournal of Food Measurement and Characterizationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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