Yazar "Çelik, Sevim Karakaş" için listeleme
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The effect of FOXO gene family variants and global DNA metylation on RRMS disease
Edgünlü, Tuba Gökdoğan; Ünal, Yasemin; Çelik, Sevim Karakaş; Genç, Öyküm; Emre, Ufuk; Kutlu, Gülnihal (Elsevier, 2020)Multiple sclerosis is a chronic disease that usually occurs with exacerbations and remissions in young adults, affects the central nervous system white matter in multiple localization, and is thought to be the result of ... -
GPR30 Gene Polymorphisms Are Associated with Gynecomastia Risk in Adolescents
Korkmaz, Hüseyin Anıl; Edgünlü, Tuba; Eren, Erdal; Demir, Korcan; Çakır, Esra Deniz Papatya; Çelik, Sevim Karakaş; Özkan, Behzat (Karger, 2015)Aim: The G protein-coupled receptor, GPR30, which is a third estrogen receptor, has been shown to mediate estrogenic effects on the essential features of human breast cancer cells. The aim of this study was to evaluate the ... -
Homozygous Ala65Pro Mutation with V89L Polymorphism in SRD5A2 Deficiency
Eren, Erdal; Edgünlü, Tuba; Asut, Emre; Çelik, Sevim Karakaş (Galenos Yayincilik, 2016)Objective: Deficiency of steroid 5-alpha reductase type 2 (5 alpha RD2) is a rare autosomal recessive disorder caused by mutations in the SRD5A2 gene. A defect in the 5-alpha reductase enzyme, which ensures conversion of ... -
Investigation of genetic variations of IL17 for vitiligo disease
Çelik, Sevim Karakaş; Tekin, Nilgün Solak; Genç, Günes Çakmak; Edgünlü, Tuba; Türkcü, Ümmühani Özel; Dursun, Ahmet (Kuwait Medical Assoc, 2019)Objective: Vitiligo is a disorder of pigmentation characterized by the presence of depigmented skin macules due to a chronic and progressive loss of melanocytes from the cutaneous epidermis. Among many different etiologic ... -
Lack of association between sirtuin gene variants and endometrial cancer
Tekin, Leyla; Edgünlü, Tuba; Çelik, Sevim Karakaş (Elsevier Science Bv, 2019)Cancer of the endometrium is the most common gynecological cancer in women. The pathophysiology of the disease has not yet been clearly defined, and the pathways leading to endometrial carcinoma are not fully understood. ...
