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Axolotl: A resourceful vertebrate model for regeneration and beyond
Bölük, Aydın; Yavuz, Mervenur; Demircan, Turan (WILEY, 2022)The regenerative capacity varies significantly among the animal kingdom. Successful regeneration program in some animals results in the functional restoration of tissues and lost structures. Among the highly regenerative ... -
In vitro anti-carcinogenic effect of andarine as a selective androgen receptor modulator on MIA-PaCa-2 cells by decreased proliferation and cell-cycle arrest at G0/G1 phase
Bölük, Aydın; Yavuz, Mervenur; Demircan, Turan; Takanlou, Maryam Sabour; Avcı, Çığır Biray (Elsevier Ltd, 2023)Pancreatic cancer (PC) continues to be devastating due to its highly malignant nature and poor prognosis. The limited benefits of the chemotherapeutic drugs and increasing resistance pose a critical challenge to overcome ... -
In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
Gökdoğan Edgünlü, Tuba; Avcı, Cigir Biray; Özateş, Neslihan Pınar; Göker Bağca, Bakiye; Karakaş Çelik, Sevim; Bölük, Aydın; Uğur, Bakiye (Bentham Science, 2021)Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ...