Yazar "Elbe, Hülya" için listeleme
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8 Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats
Elbe, Hülya; Esrefoglu, M.; Vardi, N.; Taslidere, E.; Ozerol, E.; Tanbek, K. (Sage Publications Ltd, 2015)In this study, effects of melatonin, quercetin and resveratrol on hepatocellular injury in streptozotocin (STZ)-induced experimental diabetes were aimed to be investigated by histological and biochemical methods. Thirty-five ... -
Aminoguanidine mitigates apoptosis, testicular seminiferous tubules damage, and oxidative stress in streptozotocin-induced diabetic rats
Orman, Doğan; Vardı, Nigar; Ateş, Burhan; Taşlıdere, Elif; Elbe, Hülya (Churchill Livingstone, 2015)This study aimed to investigate the effect of aminoguanidine (AG) against testicular damage streptozotocin (STZ) induced diabetes. Thirty two rats were separated into four groups: control, AG, STZ and STZ + AG. In the STZ ... -
Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells
Elbe, Hülya; Öztürk, Feral; Yiğittürk, Gürkan; Baygar, Tuba; Çavuşoğlu, Türker (TAYLOR & FRANCIS INC, 2022)Breast cancer is the most common cancer in women in the world. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Linalool is aromatic compounds from ... -
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
Elbe, Hülya; Demir M.; Altinöz E.; Koca O.; Önal M.O (Elsevier Ltd, 2023)Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR ... -
Antioxidant, anti-inflammatory, and anti-apoptotic effects of crocin against doxorubicin-induced myocardial toxicity in rats
Abdulkareem Aljumaily, Sara Asaad; Demir, Mehmet; Elbe, Hülya; Yiğittürk, Gürkan; Biçer, Yasemin; Altınöz, Eyüp (Springer, 2021)Doxorubicin (DOX) is a well-known chemotherapeutic drug for most malignancies including breast cancer and leukemia whilst the usage of DOX is limited owing to its cardiotoxicity. In the present study, we aimed to investigate ... -
Ascorbic acid and beta-carotene reduce stress-induced oxidative organ damage in rats
Esrefoğlu, M.; Akıncı, A.; Taşlıdere, E.; Elbe, Hülya; Çetin, A.; Ateş, B. (Taylor & Francis Inc, 2016)Antioxidants are potential therapeutic agents for reducing stress-induced organ damage. We investigated the effects of ascorbic acid and -carotene on oxidative stress-induced cerebral, cerebellar, cardiac and hepatic damage ... -
Beneficial effects of quercetin on renal injury and oxidative stress caused by ciprofloxacin in rats: A histological and biochemical study
Elbe, Hülya; Doğan, Z.; Taşlıdere, E.; Çetin, A.; Türköz, Y. (Sage Publications Ltd, 2016)Ciprofloxacin is a broad-spectrum quinolone antibiotic commonly used in clinical practice. Quercetin is an antioxidant belongs to flavonoid group. It inhibits the production of superoxide anion. In this study, we aimed to ... -
Cardioprotective potential of melatonin, quercetin and resveratrol in an experimental model of diabetes
Bostancıeri, N.; Elbe, Hülya; Vardı, N. (Taylor and Francis Ltd., 2021)Oxygen radicals participate in the pathogenesis of heart damage. Diabetes accelerates the formation of reactive oxygen species (ROS). We investigated the effects of the antioxidants, melatonin, quercetin and resveratrol, ... -
Comparison of ultrastructural changes and the anticarcinogenic effects of thymol and carvacrol on ovarian cancer cells: which is more effective?
Elbe, Hülya; Yiğittürk, Gürkan; Cavusoglu, Turker; Baygar, Tuba; Özgül Önal, Melike; Öztürk, Feral (Taylor & Francis Inc, 2020)Ovarian cancer is the seventh most common cancer worldwide in women. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isopropylphenol) ... -
Crocin treatment exerts anti-inflammatory and anti-oxidative effects in liver tissue damage of pinealectomized diabetic rats
Karayakalı, Melike; Altınöz, Eyüp; Elbe, Hülya; Koca, Oğuzhan; Önal, Melike Özgül; Biçer, Yasemin; Demir, Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence that leads to significant morbidity and mortality. The liver plays a vital role in glycemic regulation in physiological and ... -
Dexmedetomidine attenuates lung injury induced by liver ischemia-reperfusion injury in rats
Şahin, Taylan; Beğeç, Zekine; Elbe, Hülya; Vardi, Nigar; Durmus, Mahmut; Ersoy, M. Özcan (Scientific Publishers India, 2017)Objectives: It was aimed to evaluate histological effects of different doses of dexmedetomidine on lung injury induced by liver ischemia-reperfusion in rats. Materials and methods: Forty rats were included into the study ... -
Dexpanthenol reduces diabetic nephropathy and renal oxidative stress in rats
Tutun, B.; Elbe, Hülya; Vardı, N.; Parlakpınar, H.; Polat, A.; Günaltılı, M.; Yaşar, E. N. (Taylor & Francis Ltd, 2019)Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress contributes to the development of diabetic complications. Dexpanthenol (Dxp) is the biological active form of pantothenic acid. We ... -
Effect of a honey and arginine-glutamine-hydroxymethylbutyrate mixture on the healing of colon anastomosis in rats immunosuppressed with tacrolimus
Akbulut, S.; Dogan, Z.; Baskiran, A.; Elbe, Hülya; Turkoz, Y. (Taylor & Francis Ltd, 2019)We compared the effect of honey and a mixture of arginine-glutamine-hydroxymethylbutyrate (AGHMB) on healing of a descending colon anastomosis in rats that were immunosuppressed with tacrolimus (Tac). Sprague-Dawley rats ... -
THE EFFECT OF SAFFRON (ITS ACTIVE CONSTITUENT, CROCIN) ON THE CARDIOVASCULAR COMPLICATION AND DYSLIPIDEMIA IN STREPTOZOTOCIN INDUCED DIABETIC RATS
Altınöz, Eyüp; Taşkın, Emre; Öner, Zulal; Elbe, Hülya; Arslan, Belkis Atasever (African Networks Ethnomedicines, 2015)Background: Diabetes mellitus (DM) causes serious complications such as coronary heart disease, atherosclerosis, nephropathy, retinopathy and neuropathy. Materials and Methods: Rats were randomly divided into three groups, ... -
Effects of ciprofloxacin on fetal rat liver during pregnancy and protective effects of quercetin
Doğan, Z.; Elbe, Hülya; Taşlıdere, E.; Soysal, H.; Çetin, A.; Demirtaş, S. (Taylor & Francis Inc, 2017)Urinary tract infections are common in pregnant women and ciprofloxacin frequently is used as a broad spectrum antibiotic. It has been suggested that ciprofloxacin causes liver damage in fetuses. Quercetin is a flavonoid ... -
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction
Demir, Mehmet; Altınöz, Eyüp; Elbe, Hülya; Biçer, Yasemin; Yiğittürk, Gürkan; Karayakalı, Melike (Taylor and Francis Ltd., 2021)The present study aimed to analyze the effects of pinealectomy and crocin treatment in isoproterenol-induced myocardial damage. Seventy rats were divided into seven groups: control, sham control, pinealectomy (PNX), ... -
THE EFFECTS OF RANOLAZINE ON COBALT CHLORIDE-INDUCED CHEMICAL HYPDXIA IN ENDOTHELIAL CELLS
Çekiç, Edip Güvenç; Yiğittürk, Gürkan; Önal, Melike; Elbe, Hülya; Başaran, Nesrin Filiz; Öztürk, Feral (POLSKIE TOWARZYSTWO FARMACEUTYCZNE, 2022)Ranolazine is beneficial when given as an adjunct to treatment in symptomatic angina pectoris. Therefore, it may be useful to evaluate the effect of ranolazine on cardiovascular endothelial cells in hypoxic conditions that ... -
Effects of varenicline on lung tissue in the animal model
Ermis, Hilal; Parlakpinar, Hakan; Elbe, Hülya; Vardi, Nigar; Polat, Alaaddin; Gulbas, Gazi (Soc Brasileira Pneumologia Tisiologia, 2020)Objective: This study aimed to investigate acute and chronic effects of varenicline on lung tissue in an experimental study. Methods: A total of 34 rats were randomly allocated into study (varenicline) and control groups. ... -
Endotoxin exposure and puberty in female rats: the role of nitric oxide and caspase-1 inhibition in neonates
Özgöçer, Tuba; Yıldız, Sedat; Elbe, Hülya; Vardı, Nigar (Canadian Science Publishing, Nrc Research Press, 2015)Bacterial toxins are widespread in the environment as well as in the digestive system of humans and animals. Toxin from Gram-negative bacteria (endotoxin or lipopolysaccharide; LPS) has a life-long programming effect on ... -
Evaluation of the usage of YouTube videos about Histology and Embryology as an educational material
Çetinavcı, Dilan; Yaşar, Volkan; Yücel, Anıl; Elbe, Hülya (WILEY, 2022)The use of YouTube videos for educational purposes has been increasingly popular. The quality and accuracy of the information level of these videos should be checked by expert trainers. This study aims to evaluate the ...
