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The role of Speedy/RINGO in between MAPK and AKT pathways in SH-SY5Y neuroblastoma cells
Tanrıverdi, Özgür; Kaya, Yeşim; Küçükvardar, Seren; Yıldız, Ayşegül (Elsevier, 2020)Deregulated expression of the c-Myc oncogene is an important molecular hallmark of cancer. Previous studies have shown that the murine zinc finger protein ZF5 is a putative transcriptional regulator of c-Myc and can affect ... -
Salicylidene acylhydrazides attenuate survival of SH-SY5Y neuroblastoma cells through affecting mitotic regulator Speedy/RINGO and ERK/MAPK-PI3K/AKT signaling
Arzıman, Süleyman; Tanrıverdi, Özgür; Küçükvardar, Seren; Çitil, Neslihan; Yıldız, Ayşegül (Humana Press Inc, 2020)Salicylidene acylhydrazide group synthetic compounds ME0053, ME005 and ME0192 are known for their iron chelating properties and due to these properties they are primarily used for blocking the bacterial type 3 secretory ... -
Speedy/RINGO protein interacts with ERK/MAPK and PI3K/AKT pathways in SH-SY5Y neuroblastoma cells
Kaya, Yeşim; Küçükvardar, Seren; Yıldız, Ayşegül (Springer, 2020)Abnormal activity of ERK/MAPK and PI3K/AKT pathways is one of the most important factors for the development of many cancer types including neuroblastoma cancer. Apart from these two pathways, some cell cycle regulators ...