Yazar "Oruç-Emre, Emine Elçin" için listeleme
-
Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies
Sıcak, Yusuf; Kekeçmuhammed, Hüseyin; Karaküçük-İyidoğan, Ayşegül; Taşkın-Tok, Tuğba; Oruç-Emre, Emine Elçin; Öztürk, Mehmet (John Wiley and Sons Ltd, 2023)In this work, a series of chalcones (1a–d, 2a–d, 3a–d, 4a–d, and 5a–d) were designed and synthesized by Claisen–Schmidt condensation. Also, their chemical structures were elucidated using UV–Vis, FT IR, 1H NMR, 13C NMR, ... -
Design, in Silico Studies and Biological Evaluation of New Chiral Thiourea and 1,3-Thiazolidine-4,5-dione Derivatives
Evyapan, Samet; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet; Yılmaz Tatar, Gizem (John Wiley and Sons Inc, 2023)In this study, new chiral thiourea and 1,3-thiazolidine-4,5-dione derivatives were synthesized, it was aimed to evaluate the various biological activities and molecular docking of these compounds. Firstly, the new thioureas ... -
Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship
Karaman, Nurcan; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Çatıkkaş, Berna; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet (Springer Birkhauser, 2016)Sulfonyl hydrazone scaffold and the piperidine rings have important role in medicinal chemistry. This study shows the synthesis of two novel series of sulfonyl hydrazone having piperidine derivatives by condensing benzene ... -
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors
Karaman, Nurcan; Sıcak, Yusuf; Taşkın-Tok, Tuğba; Öztürk, Mehmet; Karaküçük-İyidoğan, Ayşegül; Dikmen, Miris; Oruç-Emre, Emine Elçin (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)Hydrazones and the piperidine ring containing compounds were considered as beneficial substrates in drug design. Therefore, this study was aimed at the synthesis of new benzoyl hydrazones derived from ethyl 4-oxopiperidi ... -
Novel fluorine-containing chiral hydrazide-hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies
Sıcak, Yusuf; Oruç-Emre, Emine Elçin; Öztürk, Mehmet; Taskın-Tok, Tuğba; Karaküçük-İyidoğan, Ayşegül (Wiley, 2019)In this study, a series of fluorine-containing chiral hydrazide-hydrazone derivatives [III-XII] from x29f; -cysteine ethyl ester hydrochloride was synthesized as new antioxidant and anticholinesterase agents. The antioxidant ... -
Synthesis, Antioxidant and Some Enzyme Inhibition Activities of New Sulfonyl Hydrazones and their Molecular Docking Simulations
Kurşun Aktar, Bedriye Seda; Sıcak, Yusuf; Tatar, Gizem; Oruç-Emre, Emine Elçin (Springer, 2022)In this work, a series of new sulfonyl hydrazones were synthesized and screened for antioxidant and anticholinesterase, tyrosinase and urease enzyme inhibition activities. In addition, molecular docking study was applied ...
