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Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model 

Hortu, İsmet; Özçeltik, Gökay; Ergenoğlu, Ahmet Mete; Yiğittürk, Gürkan; Atasoy, Özüm; Erbaş, Oytun (Springer Heidelberg, 2020)
Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ...
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Losartan ameliorates ovarian ischaemia/reperfusion injury in rats: an experimental study 

Hortu, Ismet; Ilgen, Orkun; Sahin, Cagdas; Akdemir, Ali; Yiğittürk, Gürkan; Erbas, Oytun (Taylor & Francis Inc, 2020)
This study aimed to investigate the protective and antioxidant role of losartan in ovarian ischaemia and ischaemia/reperfusion injury in an experimental ovarian torsion model. Thirty adult female rats were used. Rats were ...
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The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis: A Rat Model 

Hortu, Ismet; Ozceltik, Gokay; Karadadas, Elif; Erbas, Oytun; Yiğittürk, Gürkan; Ulukus, Murat (Springer, 2020)
To evaluate the potential effect of Ankaferd Blood Stopper (ABS) and oxytocin (OT) in an experimental endometriosis model, 18 female Sprague Dawley rats were used in this study. The animals were divided randomly into three ...
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The investigation of therapeutic potential of oxytocin and liraglutide on vincristine-induced neuropathy in rats 

Erdogan, Mumin A.; Taskiran, Emin; Yiğittürk, Gürkan; Erbas, Oytun; Taskiran, Dilek (Wiley, 2020)
The aim of this study was to assess the therapeutic potential of oxytocin and liraglutide (LIR), a GLP-1 analogue, in a rat model of vincristine-induced neuropathy. Rats were injected with vincristine (VCR) at a dose of 4 ...
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Oxytocin and cabergoline alleviate ovarian hyperstimulation syndrome (OHSS) by suppressing vascular endothelial growth factor (VEGF) in an experimental model 

Hortu, Ismet; Karadadas, Elif; Ozceltik, Gokay; Tavmergen, Erol; Tavmergen Goker, Ege Nazan; Erbas, Oytun; Yiğittürk, Gürkan (Springer Heidelberg, 2020)
Purpose Ovarian hyperstimulation syndrome (OHSS) is a life-threatening complication of ovarian stimulation in reproductive medicine. Here, we aimed to investigate the role of oxytocin (OT) and cabergoline in the prevention ...
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The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat 

Tekgul, Hasan; Simsek, Erdem; Erdogan, Mumin Alper; Yiğittürk, Gürkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2020)
Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ...
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Comparison of ultrastructural changes and the anticarcinogenic effects of thymol and carvacrol on ovarian cancer cells: which is more effective? 

Elbe, Hülya; Yiğittürk, Gürkan; Cavusoglu, Turker; Baygar, Tuba; Özgül Önal, Melike; Öztürk, Feral (Taylor & Francis Inc, 2020)
Ovarian cancer is the seventh most common cancer worldwide in women. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Thymol (5-methyl-2-isopropylphenol) ...
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Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy 

Karahan, Gökhan; Kaya, Hüseyin; Eyceyurt, Recep Selçuk; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Spandidos Publications, 2021)
The aim of the present study was to investigate the effect of dexpanthenol on nerve healing following neurorrhaphy in lacerated peripheral nerves. A total of 30 mature Sprague Dawley rats were used. Surgical sciatic nerve ...
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Anti-Inflammatory and Anti-Fibrotic Effects of Ursodeoxycholic Acid in Streptozocin-Induced Diabetic Rats 

Canbolat, İsmail Polat; Yiğittürk, Gürkan; Erbaş, Oytun (Kocaeli Derince Eğitim ve Araştırma Hastanesi, 2020)
INTRODUCTION: Diabetic cardiomyopathy is a consequence of free fatty acid oxidation, dysfunction in mitochondria, oxidative stress and diffuse myocardial fibrosis. We aimed to investigate the anti-inflammatory and anti-fibrotic ...
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Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats 

Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun; Taşkıran, Dilek (TAYLOR & FRANCIS INC, 2021)
Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ...
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