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Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship 

Karaman, Nurcan; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Çatıkkaş, Berna; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet (Springer Birkhauser, 2016)
Sulfonyl hydrazone scaffold and the piperidine rings have important role in medicinal chemistry. This study shows the synthesis of two novel series of sulfonyl hydrazone having piperidine derivatives by condensing benzene ...
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Synthesis, Antioxidant and Some Enzyme Inhibition Activities of New Sulfonyl Hydrazones and their Molecular Docking Simulations 

Kurşun Aktar, Bedriye Seda; Sıcak, Yusuf; Tatar, Gizem; Oruç-Emre, Emine Elçin (Springer, 2022)
In this work, a series of new sulfonyl hydrazones were synthesized and screened for antioxidant and anticholinesterase, tyrosinase and urease enzyme inhibition activities. In addition, molecular docking study was applied ...
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Synthesis, Characterization and Biological Evaluation of Novel Thiourea Derivatives 

Tok, Fatih; Çakır, Cansel; Çam, Dilaycan; Kırpat, Mustafa Murat; Sıcak, Yusuf (Marmara Üniversitesi, 2022)
Objective: A new series of 4-[3-(substitutedphenyl)thioureido]-N-(6-chloropyrazin-2-yl)benzenesulfonamide were synthesized from sulfaclozine. Methods: All compounds were characterized by IR, 1H-NMR spectroscopic methods ...
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Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies 

Sıcak, Yusuf; Kekeçmuhammed, Hüseyin; Karaküçük-İyidoğan, Ayşegül; Taşkın-Tok, Tuğba; Oruç-Emre, Emine Elçin; Öztürk, Mehmet (John Wiley and Sons Ltd, 2023)
In this work, a series of chalcones (1a–d, 2a–d, 3a–d, 4a–d, and 5a–d) were designed and synthesized by Claisen–Schmidt condensation. Also, their chemical structures were elucidated using UV–Vis, FT IR, 1H NMR, 13C NMR, ...



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Sıcak, Yusuf (4)
Oruç-Emre, Emine Elçin (3)Karaküçük-İyidoğan, Ayşegül (2)Öztürk, Mehmet (2)Karaman, Nurcan (1)Kekeçmuhammed, Hüseyin (1)Kurşun Aktar, Bedriye Seda (1)Kırpat, Mustafa Murat (1)Tatar, Gizem (1)Taşkın-Tok, Tuğba (1)... View MoreSubject
Antioxidant (4)
Anticholinesterase (3)Tyrosinase (3)Molecular docking (2)Urease (2)Alzheimer's (1)Chalcone (1)DFT Calculations (1)Piperidine (1)Sulfonyl hydrazine (1)... View MoreDate Issued2022 (2)2016 (1)2023 (1)Full Text StatusWith Full Text (4)

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