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dc.contributor.authorDuru, Mehmet Emin
dc.contributor.authorEroğlu, Büşra
dc.contributor.authorTel-Çayan, Gülsen
dc.contributor.authorTaş-Küçükaydın, Meltem
dc.contributor.authorKüçükaydın, Selçuk
dc.contributor.authorÇayan, Fatih
dc.contributor.authorCeylan, Özgür
dc.date.accessioned2023-06-13T10:46:55Z
dc.date.available2023-06-13T10:46:55Z
dc.date.issued2023en_US
dc.identifier.citationDuru, M. E., Eroğlu, B., Tel-Çayan, G., Taş-Küçükaydın, M., Küçükaydın, S., Çayan, F., & Ceylan, Ö. (2023). HPLC‐DAD analysis and versatile bioactivities of Turkish sunflower honeys using chemometric approaches. Chemistry & Biodiversity, e202300486.en_US
dc.identifier.issn16121872
dc.identifier.urihttps://hdl.handle.net/20.500.12809/10782
dc.description.abstractSunflower honey (SH) is bright yellow, fragrant, pollen-flavoured, slightly herbaceous and has a unique taste. The present research aims to examine the enzyme inhibitory, antioxidant, anti-inflammatory, antimicrobial and anti-quorum sensing activities and phenolic compositions of 30 sunflower honeys (SHs) produced from several regions of Turkey with chemometric study. SAH from Samsun exhibited the best antioxidant activity in β-carotene linoleic acid (IC50: 7.33±0.17 mg/mL) and CUPRAC (A0.50: 4.94±0.13 mg/mL) assays, anti-urease activity (60.63±0.87 %) and anti-inflammatory activity against COX-1 (73.94±1.08 %) and COX-2 (44.96±0.85 %). SHs exhibited mild antimicrobial activity against the test microorganisms while they showed high quorum sensing inhibition zones measured in the range of 42–52 mm against the CV026 strain. The phenolic composition was determined by high performance liquid chromatography with diode array detection (HPLC-DAD) system and levulinic, gallic, p-hydroxybenzoic, vanillic and p-coumaric acids were identified in all studied SHs. The classification of SHs was performed the using PCA and HCA. This study revealed that phenolic compounds and biological properties are effective in classification of SHs according to their geographical origin. The results suggest that studied SHs could be valued as potential agents with versatile bioactivities in oxidative stress-related disease, microbial infections, inflammation, melanoma, and peptic ulcer.en_US
dc.item-language.isoengen_US
dc.publisherJohn Wiley and Sons Incen_US
dc.relation.isversionof10.1002/cbdv.202300486en_US
dc.item-rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiological activityen_US
dc.subjectChemometric studyen_US
dc.subjectHPLC-DADen_US
dc.subjectPhenolic compositionen_US
dc.titleHPLC-DAD Analysis and Versatile Bioactivities of Turkish Sunflower Honeys Using Chemometric Approachesen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Fen Fakültesi, Kimya Bölümüen_US
dc.contributor.authorID0000-0001-7252-4880en_US
dc.contributor.authorID0000-0002-1916-7391en_US
dc.contributor.authorID0000-0001-8538-6528en_US
dc.contributor.authorID0000-0003-2397-8071en_US
dc.contributor.authorID0000-0002-1865-1093en_US
dc.contributor.institutionauthorDuru, Mehmet Emin
dc.contributor.institutionauthorEroğlu, Büşra
dc.contributor.institutionauthorTel-Çayan, Gülsen
dc.contributor.institutionauthorTaş-Küçükaydın, Meltem
dc.contributor.institutionauthorKüçükaydın, Selçuk
dc.contributor.institutionauthorÇayan, Fatih
dc.contributor.institutionauthorCeylan, Özgür
dc.relation.journalChemistry and Biodiversityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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