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Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model
(Springer Heidelberg, 2020)
Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ...
Investigation of genetic variations of IL17 for vitiligo disease
(Kuwait Medical Assoc, 2019)
Objective: Vitiligo is a disorder of pigmentation characterized by the presence of depigmented skin macules due to a chronic and progressive loss of melanocytes from the cutaneous epidermis. Among many different etiologic ...
The role of antioxidant vitamins and selenium in patients with obstructive sleep apnea
(Springer Heidelberg, 2020)
Purpose Obstructive sleep apnea (OSA) is a disorder characterized by recurrent episodes of obstruction of the upper respiratory tract during sleep often accompanied by oxygen desaturations. Antioxidant defense mechanisms ...
The Effect of Sildenafil on Selenite-Induced Cataract in Rats
(Taylor & Francis Inc, 2020)
Purpose: To investigate the effect of sildenafil on an experimental sodium selenite-induced cataract model in rats. Materials and Methods: Twenty-six young Wistar rats were separated into four groups. On postpartum day 10, ...
Evaluation of the neuroprotective effects of ozone in an experimental spine injury model
(Amer Assoc Neurological Surgeons, 2020)
OBJECTIVE The pathophysiology of spine injury consists of primary and secondary damage mechanisms. The vast majority of treatments aim to prevent or at least stop the progression of secondary neurotoxic events during the ...
The effect of FOXO gene family variants and global DNA metylation on RRMS disease
(Elsevier, 2020)
Multiple sclerosis is a chronic disease that usually occurs with exacerbations and remissions in young adults, affects the central nervous system white matter in multiple localization, and is thought to be the result of ...
Microbiome and Longevity: High Abundance of Longevity-Linked Muribaculaceae in the Gut of the Long-Living RodentSpalax leucodon
(Mary Ann Liebert, Inc, 2020)
With a world population living longer as well as marked disparities in life expectancy, understanding the determinants of longevity is one of the priority research agendas in 21st century life sciences. To this end, the ...
Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel
(Taylor & Francis Ltd, 2017)
Background: In breast cancers, calcium signaling is a main cause of proliferation and apoptosis of breast cancer cells. Although previous studies have implicated the transient receptor potential vanilloid 1 (TRPV1) cation ...
The apoptotic effects of silibinin on MDA-MB-231 and MCF-7 human breast carcinoma cells
(Sage Publications Ltd, 2017)
Background: Silibinin is a bioactive flavonolignan extracted from milk thistle, known as Silybum marianum. Silibinin exerts strong antiproliferative, proapoptotic, and anti-inflammatory effects. Many studies have shown ...
Protein Oxidation Levels After Different Corneal Collagen Cross-Linking Methods
(Lippincott Williams & Wilkins, 2016)
Purpose: To evaluate advanced oxidation protein products (AOPP) levels, superoxide dismutase (SOD) enzyme activity, and total sulfhydryl (TSH) levels in rabbit corneas after different corneal collagen cross-linking (CXL) ...