Ara
Toplam kayıt 33, listelenen: 21-30
Treatment with crocin suppresses diabetic nephropathy progression via modulating TGF-β1 and oxidative stress in an experimental model of pinealectomized diabetic rats
(Elsevier, 2022)
One of the most common complications of diabetes is diabetic nephropathy (DN). Uncontrolled hyperglycemia leads to histopathologic alterations in the kidney that prevent normal renal function. This study aimed to explore ...
Influence of Pinealectomy and Long-term Melatonin Administration on Inflammation and Oxidative Stress in Experimental Gouty Arthritis
(Springer, 2022)
Gout is an inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints or soft tissue. MSU crystals are potent inflammation inducers. Melatonin (MLT) is a powerful endogenous ...
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction
(Taylor and Francis Ltd., 2021)
The present study aimed to analyze the effects of pinealectomy and crocin treatment in isoproterenol-induced myocardial damage. Seventy rats were divided into seven groups: control, sham control, pinealectomy (PNX), ...
Anticancer activity of linalool: comparative investigation of ultrastructural changes and apoptosis in breast cancer cells
(TAYLOR & FRANCIS INC, 2022)
Breast cancer is the most common cancer in women in the world. Many anticancer drugs are currently used clinically have been isolated from plant species or are based on such substances. Linalool is aromatic compounds from ...
Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis
(TURKISH LEAGUE AGAINST RHEUMATISM, 2022)
Objectives: In this study, we aimed to investigate the differentiation potential of dental follicle mesenchymal stem cells (MSCs) in the synovial fluid (SF) niche of early-onset or end-stage rheumatoid arthritis (RA). ...
THE EFFECTS OF RANOLAZINE ON COBALT CHLORIDE-INDUCED CHEMICAL HYPDXIA IN ENDOTHELIAL CELLS
(POLSKIE TOWARZYSTWO FARMACEUTYCZNE, 2022)
Ranolazine is beneficial when given as an adjunct to treatment in symptomatic angina pectoris. Therefore, it may be useful to evaluate the effect of ranolazine on cardiovascular endothelial cells in hypoxic conditions that ...
Evaluation of the usage of YouTube videos about Histology and Embryology as an educational material
(WILEY, 2022)
The use of YouTube videos for educational purposes has been increasingly popular. The quality and accuracy of the information level of these videos should be checked by expert trainers. This study aims to evaluate the ...
Pinealectomy and melatonin administration in rats: their effects on pulmonary edema induced by alpha-naphthylthiourea
(TAYLOR & FRANCIS LTD, 2022)
We aimed to observe the possible effects of melatonin (MLT) deprivation (pinealectomy) and exogenous MLT administration on pulmonary edema induced by alpha-naphthylthiourea (ANTU), a toxic chemical agent, in rats. Seventy ...
Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats
(Elsevier B.V., 2022)
The current study aimed to evaluate the neuroprotective effect of exogenous melatonin against acrylamide (ACR)-induced oxidative stress and inflammatory and apoptotic responses in the brain tissues in pinealectomized rats ...
Leptin Accelerates Endothelial Wound Healing: Role of Endothelial Nitric Oxide Synthase Expression
(Turkish Society of Cardiology, 2022)
Background: The endothelium is crucial for the control of vascular homeostasis and plays a role in angiogenesis. Leptin, a protein released mainly by adipose tissue, plays a key role in the regulation of energy balance and ...