Ara
Toplam kayıt 68, listelenen: 61-68
Host-Induced Gene Silencing: Approaches in Plant Disease Management
(Springer International Publishing, 2023)
Crops exposed to the damage of various biotic and abiotic sources result in reduced yields and cause economic losses. There are prominent strategies such as breeding for improved resistance, the application of pesticides, ...
Adjuvant composite cold atmospheric plasma therapy increases antitumoral effect of doxorubicin hydrochloride
(PMC, 2023)
Introduction: Cancer is a global health concern, with a significant impact on mortality rates. Despite advancements in targeted antitumor drugs, the development of new therapies remains challenging due to high costs and ...
A potential posttranscriptional regulator for p60-katanin: miR-124-3p
(John Wiley and Sons Inc, 2023)
Katanin is a microtubule severing protein belonging to the ATPase family and consists of two subunits; p60-katanin synthesized by the KATNA1 gene and p80-katanin synthesized by the KATNB1 gene. Microtubule severing is one ...
A new species of Saxifraga (Saxifragaceae) from northeastern Anatolia, Turkey
(Magnolia Press, 2023)
Saxifraga kavrunensis, a new species endemic to Turkey, is described and illustrated. Samples from its natural population were collected from the Kaçkar Mountains in Rize Province. Although it has similar features to S. ...
Data mining and molecular dynamics analysis to detect HIV-1 reverse transcriptase RNase H activity inhibitor
(nstitute for Ionics, 2023)
HIV-1 is a deadly virus that affects millions of people worldwide. In this study, we aimed to inhibit viral replication by targeting one of the HIV-1 proteins and identifying a new drug candidate. We used data mining and ...
A new 1,2,4-triazine-n-oxide compound: Synthesis, crystal structure, Hirshfeld surface analysis and supercapacitor applications
(Elsevier B.V., 2023)
In this paper, we report the one-step, metal catalyst-free synthesis of 6-(4-chlorophenyl)-3,3-dimethyl-4-(N-oxide)-1,2,3,4-tetrahydro-1,2,4-triazine using 2,4-dihydroxyacetophenone and p‑chloro isonitrosophenyl hydrazine ...
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
(Springer Science and Business Media Deutschland GmbH, 2023)
Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ...
Targeting MDM2-p53 Axis through Drug Repurposing for Cancer Therapy: A Multidisciplinary Approach
(PMC, 2023)
Cancer remains a major cause of morbidity and mortality worldwide, and while current therapies, such as chemotherapy, immunotherapy, and cell therapy, have been effective in many patients, the development of novel therapeutic ...