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dc.contributor.authorYılmaz, Nevin
dc.contributor.authorZeybek, Arife
dc.contributor.authorTharian, Benjamin
dc.contributor.authorYilmaz, Ugur Eser
dc.date.accessioned2020-11-20T16:17:41Z
dc.date.available2020-11-20T16:17:41Z
dc.date.issued2015
dc.identifier.issn2198-7793
dc.identifier.urihttps://doi.org/10.1186/s40792-015-0049-x
dc.identifier.urihttps://hdl.handle.net/20.500.12809/3320
dc.descriptionWOS: 000218398700062en_US
dc.descriptionPubMed ID: 26366359en_US
dc.description.abstractChemical pleurodesis is one of the therapeutic tools to control hepatic hydrothorax. Tetracycline and derivatives have been widely accepted as an effective and safe treatment for the purpose, but availability is the big concern. Tigecycline is an antibiotic derivative of tetracycline, which has demonstrated to be an effective pleurodesing agent in animal models. The aim of the study was to document two successful tigecycline pleurodesis in patients with decompensated liver cirrhosis, who were not candidates for liver transplantation. Both patients were undergoing palliative treatment for cirrhosis and developed massive pleural effusion on the right side. They underwent chemical pleurodesis in the first instance. Diagnostic thoracocentesis was done to rule out differentials and to confirm the clinical suspicion, following which, complete drainage of pleural fluids was achieved. Tigecycline of 3 mg/kg was instilled intrapleurally via the thoracic catheter, as per the protocol. The medical records and images were thoroughly reviewed. There was no recurrence of the effusion for at least 3 months, with no detected complications in the short- or long-term follow-up. In conclusion, pleurodesis with tigecycline seems to be effective and safe for the management of symptomatic hepatic hydrothorax and should therefore be promoted in the setting of liver cirrhosis at least for a short-term relief, especially in patients who do not meet the criteria for liver transplantation.en_US
dc.item-language.isoengen_US
dc.publisherSpringer Japan Kken_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSurgeryen_US
dc.titleEfficacy of nonsurgical tigecycline pleurodesis for the management of hepatic hydrothorax in patients with liver cirrhosisen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Eğitim ve Araştırma Hastanesien_US
dc.contributor.institutionauthorYılmaz, Nevin
dc.contributor.institutionauthorZeybek, Arife
dc.identifier.doi10.1186/s40792-015-0049-x
dc.identifier.volume1en_US
dc.relation.journalSurgical Case Reportsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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