Experimental design applications in chemistry: A case study on Central composite design for optimization of extraction of olive seeds in a Soxhlet
Özet
Chemometrics is described in general as to extract the more useful information from the chemical data obtained experimentally by various methods applying some mathematical techniques to these data. Today, studies in many fields such as chemistry, biochemistry, earth, and environmental sciences are done experimentally and all analysis of semi-finished and finished products or raw materials for quality control are carried out in the laboratories. Establishment of test strategies for experimental design, analysis of experimental design models and optimization of the experimental factors of a reaction selected as a practical application for experimental design are the main subjects of this study. Here it was summarized creation of experiment strategies in order to optimize the effective operation factors on chemical reactions, mathematical solution techniques of the response surface functions to define the relationships between the factors and the experimental result affected by the factors, computer programing for the optimization of the reaction parameters and usage of some related software, statistically evaluation for the experimental results and optimization of a selected reaction as an experimental design application. © 2019, © 2019 Taylor & Francis Group, LLC.
