• Biosynthesis, characterization, and investigation of antimicrobial and cytotoxic activities of silver nanoparticles using Solanum tuberosum peel aqueous extract 

  Xu, Jiajun; Yıldıztekin, Mahmut; Han, Dayong; Keskin, Cumali (ELSEVIER SCI LTD, 2023)

  Metallic nanoparticle biosynthesis is thought to offer opportunities for a wide range of biological uses. The green process of turning biological waste into utilizable products gaining attention due to its economical and ...

• Effects of Hypericum perforatum extract on 6-hydroxydopamine neurotoxicity in differentiated SH-SY5Y cells 

  Bitmez, Barış; Gültekin, Seda; Albayrak, İrem; Deveci, Yiğit; Sıcak, Yusuf; Akalın, Emine (EGYPTIAN PHARMACEUTICAL JOURNAL, 2023)

  Background and objectiveParkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. In our study, PD model was created as a result of exposure to 6-hydroxydopamine (6-OHDA) in ...

• Green synthesis and evaluation of antipathogenic, antioxidant, and anticholinesterase activities of gold nanoparticles (Au NPs) from Allium cepa L. peel aqueous extract 

  İpek, Polat; Baran, Mehmet Fırat; Baran, Ayşe; Hatipoğlu, Abdülkerim; Keskin, Cumali; Yıldıztekin, Mahmut (Springer Science and Business Media Deutschland GmbH, 2023)

  Gold nanoparticles (Au NPs) have potentially therapeutic properties as they are synthesized via biomolecules as reducing and stabilizing agent(s). The aim of this study is to develop an easy and eco-friendly method for the ...

• Betanin and Nano-Calcium Carbonate Incorporated Polyvinyl alcohol/Starch Films for Active and Intelligent Packaging Applications 

  Kavas, Eslem; Terzioğlu, Pınar; Sıcak, Yusuf (Springer, 2023)

  Bio-based and biodegradable packaging are ideal for sustainable polymer packaging. In this study, cassava starch and polyvinyl alcohol (PVA) were used as the film-forming matrix, betanin (E-162) and nano-calcium carbonate ...

• Chalcones bearing nitrogen-containing heterocyclics as multi-targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies 

  Sıcak, Yusuf; Kekeçmuhammed, Hüseyin; Karaküçük-İyidoğan, Ayşegül; Taşkın-Tok, Tuğba; Oruç-Emre, Emine Elçin; Öztürk, Mehmet (John Wiley and Sons Ltd, 2023)

  In this work, a series of chalcones (1a–d, 2a–d, 3a–d, 4a–d, and 5a–d) were designed and synthesized by Claisen–Schmidt condensation. Also, their chemical structures were elucidated using UV–Vis, FT IR, 1H NMR, 13C NMR, ...

• Green Synthesis of Silver Nanoparticles from Allium cepa L. Peel Extract, Their Antioxidant, Antipathogenic, and Anticholinesterase Activity 

  Baran , Mehmet Fırat; Keskin, Cumali; Baran, Ayşe; Hatipoğlu, Abdülkerim; Yıldıztekin, Mahmut (MDPI, 2023)

  The present work deals with the green synthesis and characterization of silver nanoparticles (AgNPs) using Allium cepa (yellowish peel) and the evaluation of its antimicrobial, antioxidant, and anticholinesterase activities. ...

• Investigation of antioxidant properties, essential oil, and fatty acid composition of Onobrychisarmena Boiss. & Huet 

  Karataş, Şükrü; Aktümsek, Abdurrahman; Uysal, Şengül (Istanbul University, 2022)

  Background and Aims: In this study, Onobrcyhis armena BOISS. & HUET was screened for its antioxidant potential, fatty acids and volatile compounds. Methods: Antioxidant activities of different extracts (ethylacetate, ...

• Synthesis, Antioxidant and Some Enzyme Inhibition Activities of New Sulfonyl Hydrazones and their Molecular Docking Simulations 

  Kurşun Aktar, Bedriye Seda; Sıcak, Yusuf; Tatar, Gizem; Oruç-Emre, Emine Elçin (Springer, 2022)

  In this work, a series of new sulfonyl hydrazones were synthesized and screened for antioxidant and anticholinesterase, tyrosinase and urease enzyme inhibition activities. In addition, molecular docking study was applied ...

• Synthesis, predictions of drug-likeness, and pharmacokinetic properties of some chiral thioureas as potent enzyme inhibition agents 

  Sıcak, Yusuf (SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2022)

  A series of chiral thioureas (1 - 17) were synthesized from and tested for their anticholinesterase, tyrosinase, and urease enzyme inhibitor activities. Various phenylisothiocyanates were added to solution of ??-cysteine ...

• Synthesis of benzoyl hydrazones having 4-hydroxy-3,5-dimethoxy phenyl ring, their biological activities, and molecular modeling studies on enzyme inhibition activities 

  Kurşun Aktar, Bedriye Seda; Sıcak, Yusuf; Tatar, Gizem; Oruç Emre, Emine Elçin (SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2021)

  Hydrazone compounds such as anticholinesterase, tyrosinase, and urease have high capacity in terms of antioxidant activity and enzyme inhibition activities. In this study, benzoyl hydrazones compounds (7a-7m) were synthesized ...

• Scutellaria topcuoglui (Lamiaceae), a new serpentinomorph species from south-western Anatolia, Turkey 

  Yıldırım, Hasan; Çiçek, Mehmet; Akbaş, Kenan; Şeker, Erkan (MAGNOLIA PRESS, 2021)

  Scutellaria topcuoglui (Lamiaceae) from Mugla Province (south-western Anatolia) is described as a new species to science. The new species is morphologically similar to S. glaphyrostachys, but differs from it by several ...

• An investigation of the biological activity of monofloral honey produced in south-western Anatolia 

  Karataş, Şükrü; Aktümsek, Abdurrahman; Duru, Mehmet Emin (2021)

  In this study, monofloral honeys (chaste, thyme, citrus, and heather) which were obtained from different sources from members of Beekeeping Associations in South-West Anatolia were studied for their antioxidant capacity, ...

• CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OIL OF CITRUS SINENSIS: INTERACTION WITH AMPICILLIN AND FLUCONAZOLE 

  Erdoğan Eliuz, Elif Ayşe; Yabalak, Erdal; Sıcak, Yusuf (EDITURA ACAD ROMANE, 2020)

  In the present study, the interactions of essential oil (EO) of Citrus sinensis L. Osbeck with two antibiotics (ampicillin and fluconazole), which are commonly used in the treatment of infections, were investigated. C. ...

• Design and Antiproliferative and Antioxidant Activities of Furan-Based Thiosemicarbazides and 1,2,4-Triazoles: Their Structure-Activity Relationship and SwissADME Predictions 

  Sıcak, Yusuf (Springer, 2021)

  Due to the limited number of drugs in current clinical use, the diverse biological applications of furan have encouraged the preparation of a wide variety of thiosemicarbazide and triazole derivatives for the purpose of ...

• Bioactivities and phenolic constituents relationship of Muğla thyme and pine honey of Turkey with the chemometric approach 

  Sıcak, Yusuf; Şahin Yağlıoğlu, Ayşe; Öztürk, Mehmet (Springer, 2021)

  The chemical ingredients of pine and thyme honey were studied, along with their medicinal activity properties. A method was validated for common honey compounds using LC-TOF/MS to analyze the ingredients. In vitro ...

• Ameliorative effects of exogenous ascorbic acid and potassium nitrate on antioxidant defense system and mineral nutrient uptake in tomatoes under salt stress 

  Yıldıztekin, Mahmut (Pakistan Botanical Society, 2021)

  The aim of this study was to analyze the effects of ascorbic acid (AsA) and potassium nitrate (KNO3) on the salt-based oxidative stress in Lycopersicon esculentum Mill. leaves. The obtained results showed that the saline ...

• OXIDATIVE STRESS AND ANTIOXIDATIVE MECHANISMS IN TOMATO (SOLANUM LYCOPERSICUM L.) PLANTS SPRAYED WITH DIFFERENT PESTICIDES 

  Yıldıztekin, Mahmut; Kaya, Cengiz; Tuna, Atilla Levent; Ashraf, Muhammed (Pakistan Botanical Soc, 2015)

  A glasshouse experiment was conducted to appraise the influence of exogenously applied pesticides such as abamectin, thiamethoxam, pyriproxyfen and acetamiprid on oxidative defence system and some key physiological attributes ...

• Microwave-assisted synthesis of new sulfonyl hydrazones, screening of biological activities and investigation of structure-activity relationship 

  Karaman, Nurcan; Oruç-Emre, Emine Elçin; Sıcak, Yusuf; Çatıkkaş, Berna; Karaküçük-İyidoğan, Ayşegül; Öztürk, Mehmet (Springer Birkhauser, 2016)

  Sulfonyl hydrazone scaffold and the piperidine rings have important role in medicinal chemistry. This study shows the synthesis of two novel series of sulfonyl hydrazone having piperidine derivatives by condensing benzene ...

• New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors 

  Karaman, Nurcan; Sıcak, Yusuf; Taşkın-Tok, Tuğba; Öztürk, Mehmet; Karaküçük-İyidoğan, Ayşegül; Dikmen, Miris; Oruç-Emre, Emine Elçin (Elsevier France-Editions Scientifiques Medicales Elsevier, 2016)

  Hydrazones and the piperidine ring containing compounds were considered as beneficial substrates in drug design. Therefore, this study was aimed at the synthesis of new benzoyl hydrazones derived from ethyl 4-oxopiperidi ...

• INVESTIGATIONS ON THE EFFECTS OF COMMONLY USED PESTICIDES ON TOMATO PLANT GROWTH 

  Yıldıztekin, Mahmut; Özler, Mehmet Ali; Nadeem, Said; Tuna, Atilla Levent (Parlar Scientific Publications (P S P), 2019)

  Acetamiprid (ABA), imidacloprid (IM), abamectin (ABA), thiomethoxam (THM) and abamectin+chlorantraniliprole (ABAC) were applied on Hazera 5656 F1 (Lycopersicum esculentum Mill.) tomato variety under greenhouse conditions ...

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