Yazar "Yiğittürk, Gürkan" için listeleme
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The neuro-restorative effect of adipose-derived mesenchymal stem cell transplantation on a mouse model of diabetic neuropathy
Yiğittürk, Gürkan; Erbaş, Oytun; Karabay Yavaşoğlu, Nefise Ülkü; Açıkgöz, Eda; Buhur, Aylin (Taylor and Francis Ltd., 2021)Diabetic neuropathy (DN) is the most common degenerative complication associated with Diabetes Mellitus. Despite widespread awareness about DN, the only effective treatments are blood glucose control and pain management. ... -
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun; Taşkıran, Dilek (TAYLOR & FRANCIS INC, 2021)Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ... -
Oxidative stress-induced apoptotic changes after acute exposure to antifouling agent zinc pyrithione (ZnPT) in Mytilus galloprovincialis Lamark (Mediterranean mussels) tissues
Kataloay, Selma; Güner, Adem; Dağdeviren, Melih; Yiğittürk, Gürkan; Yavaşoğlu, Altuğ; Günal, A. Çağlan (TAYLOR & FRANCIS LTD, 2022)Zinc pyrithione (ZnPT) is one of the components used in antifouling paints and can be an alternative to classical toxic chemicals such as organotin. However, there is still remarkable concern about the environmental safeness ... -
Oxytocin and cabergoline alleviate ovarian hyperstimulation syndrome (OHSS) by suppressing vascular endothelial growth factor (VEGF) in an experimental model
Hortu, Ismet; Karadadas, Elif; Ozceltik, Gokay; Tavmergen, Erol; Tavmergen Goker, Ege Nazan; Erbas, Oytun; Yiğittürk, Gürkan (Springer Heidelberg, 2020)Purpose Ovarian hyperstimulation syndrome (OHSS) is a life-threatening complication of ovarian stimulation in reproductive medicine. Here, we aimed to investigate the role of oxytocin (OT) and cabergoline in the prevention ... -
Possibility of Taking an Offensive Stance in Extravasation Injury: Effects of Fat Injection in Vesicant (Doxorubicin) Induced Skin Necrosis Model in Rats
Biçer, Ahmet; Erçin, Burak Sercan; Gürler, Tahir; Yiğittürk, Gürkan; Uyanıkgil, Yiğit; Çetin, Emel Öykü (Taylor and Francis Ltd., 2021)Introduction: Extravasation injuries are one of the most feared complications of intravenous drug administration. The most common drugs associated with extravasation injury include chemotherapy agents and contrast media. ... -
The potential effects of anticonvulsant drugs on neuropeptides and neurotrophins in pentylenetetrazol kindled seizures in the rat
Tekgul, Hasan; Simsek, Erdem; Erdogan, Mumin Alper; Yiğittürk, Gürkan; Erbas, Oytun; Taskiran, Dilek (Taylor & Francis Ltd, 2020)Purpose: Neuropeptides and neurotrophic factors are thought to be involved in epileptogenesis. This study aims to investigate the potential effects of anticonvulsant drugs on neuropeptides (galanin and neuropeptide Y) and ... -
Protective effect of oxytocin on a methotrexate-induced ovarian toxicity model
Hortu, İsmet; Özçeltik, Gökay; Ergenoğlu, Ahmet Mete; Yiğittürk, Gürkan; Atasoy, Özüm; Erbaş, Oytun (Springer Heidelberg, 2020)Purpose Although cancer predominantly affects people at older ages, a substantial number of patients, like breast cancer patients, are diagnosed before they have completed their families or even before giving birth. ... -
Protective effects of sildenafil and resveratrol on ovarian ischemiareperfusion injury in rats
Ertürk, Nazile; Elbe, Hülya; Erdemli, Mehmet Erman; Aktas, Serdar; Yiğittürk, Gürkan; Aksungur, Zeynep; Öztürk, Feral; Süzen, Alev (Scientific Publishers of India, 2017)Aim: This study investigated the protective effects of sildenafil (SIL) and resveratrol (RSV) on ovarian ischemia-reperfusion (I/R) injury. Materials and methods: Forty-Eight Wistar albino rats were divided equally into ... -
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
Gürkan, Gökhan; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Korean Neurosurgical Society, 2021)Objective: Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ... -
The Role of Ankaferd Blood Stopper and Oxytocin as Potential Therapeutic Agents in Endometriosis: A Rat Model
Hortu, Ismet; Ozceltik, Gokay; Karadadas, Elif; Erbas, Oytun; Yiğittürk, Gürkan; Ulukus, Murat (Springer, 2020)To evaluate the potential effect of Ankaferd Blood Stopper (ABS) and oxytocin (OT) in an experimental endometriosis model, 18 female Sprague Dawley rats were used in this study. The animals were divided randomly into three ... -
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
Bora, Ejder Saylav; Erdoğan, Arife; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Çakır, Adem; Erbaş, Oytun (URKISH ASSOC TRAUMA EMERGENCY SURGERY, 2022)BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ... -
Synovial fluid niche promoted differentiation of dental follicle mesenchymal stem cells toward chondrogenesis in rheumatoid arthritis
Genç, Deniz; Sezer Kürkçü, Merve; Yiğittürk, Gürkan; Günaydın, Burcu; Elbe, Hülya; Aladağ, Akın; Çöl, Bekir; Tarhan, Emine Figen (TURKISH LEAGUE AGAINST RHEUMATISM, 2022)Objectives: In this study, we aimed to investigate the differentiation potential of dental follicle mesenchymal stem cells (MSCs) in the synovial fluid (SF) niche of early-onset or end-stage rheumatoid arthritis (RA). ... -
Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study
Taşkıran, Emin; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Humana Press Inc, 2019)Doxorubicin-induced (DXR) cardiomyopathy is a serious health issue in oncology patients. Effective treatment of this clinical situation still remains to be discovered. In this experimental animal study, we aimed to define ... -
Treatment with crocin suppresses diabetic nephropathy progression via modulating TGF-β1 and oxidative stress in an experimental model of pinealectomized diabetic rats
Keelo, Rihab Mudhafar Ali Hammood; Elbe, Hülya; Biçer, Yasemin; Yiğittürk, Gürkan; Koca, Oğuzhan; Karayakalı, Melike; Acar, Derya; Altınöz, Eyüp (Elsevier, 2022)One of the most common complications of diabetes is diabetic nephropathy (DN). Uncontrolled hyperglycemia leads to histopathologic alterations in the kidney that prevent normal renal function. This study aimed to explore ...