Kurum Yazarı "Varol, Mehmet" İçin Listeleme
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Photodynamic therapy assay
Varol, Mehmet (Humana Press Inc., 2020)Photodynamic therapy is a promising, minimally invasive, and clinically approved treatment strategy that destroys the cell components by oxidizing the biological molecules such as nucleic acids, carbohydrates, proteins, ... -
Photoprotective activity assay toward ultraviolet B in human keratinocytes
Varol, Mehmet (Humana Press Inc., 2020)Design and discovery of novel sunscreens are of great importance to protect the human skin toward ultraviolet-induced damages because of the incidence of skin cancers that is believed to have increased depending on the ... -
Photoprotective Activity of Vulpinic and Gyrophoric Acids Toward Ultraviolet B-Induced Damage in Human Keratinocytes
Varol, Mehmet; Türk, Aysen; Candan, Mehmet; Tay, Turgay; Koparal, Ayşe Tansu (Wiley, 2016)Vulpinic and gyrophoric acids are known as ultraviolet filters for natural lichen populations because of their chemical structures. However, to the best of our knowledge, there has been no reference to their cosmetic ... -
Polymer-mediated nanoformulations: a promising strategy for cancer immunotherapy
Kaur, Simranjit; Saini, Adesh K.; Tuli, Hardeep Singh; Garg, Nancy; Joshi, Hemant; Varol, Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)Engineering polymer-based nano-systems have attracted many researchers owing to their unique qualities like shape, size, porosity, mechanical strength, biocompatibility, and biodegradability. Both natural and synthetic ... -
Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
Aggarwal, Vaishali; Tuli, Hardeep Singh; Varol, Ayşegül; Thakral, Falak; Yerer, Mükerrem Betül; Sak, Katrin; Sethi, Gautam; Varol, Mehmet (Mdpi, 2019)Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous ROS production in normal cells is controlled by the appropriate regulation between the silver lining of low and high ROS concentration ... -
STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation
Tuli, Hardeep Singh; Sak, Katrin; Iqubal, Ashif; Garg, Vivek Kumar; Varol, Mehmet; Sharma, Uttam (SPRINGER, 2022)As a landmark, scientific investigation in cytokine signaling and interferon-related anti-viral activity, signal transducer and activator of transcription (STAT) family of proteins was first discovered in the 1990s. Today, ... -
Synthesis, Structural Investigations, and In Vitro/In Silico Bioactivities of Flavonoid Substituted Biguanide: A Novel Schiff Base and Its Diorganotin (IV) Complexes
Abbas, Zahoor; Kumar, Manoj; Tuli, Hardeep Singh; M Janahi, Essam; Haque, Shafiul ; Harakeh, Steve; Varol, Mehmet (MDPI, 2022)Quercetin is one of the most powerful bioactive dietary flavonoids. The in vivo biological study of quercetin is extremely difficult due to its very low solubility. However, diorganotin complexes of quercetin are more ... -
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential
Tuli, Hardep S; Aggarwal, Vaishali; Parashar, Gaurav; Aggarwal, Diwakar; Parashar, Nidarshana C; Tuorkey, Muobarak J; Varol, Mehmet; Sak, Katrin; Kumar, Manoj; Buttar, Harpal S. (Bentham Science Publishers, 2021)The overwhelming globalburden of cancer has posed numerous challenges and opportunities for developing anti-cancer therapies. Phytochemicalshave emerged as promising synergistic compounds with potential anti-cancer effects ...