Yazar "Alper, Mehlika" için listeleme
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The Anticancer and Anti-inflammatory Effects of Centaurea solstitialis Extract on Human Cancer Cell Lines
Alper, Mehlika; Güneş, Hatice (Turkish Pharmacists Assoc, 2019)Objectives: Natural products originating from plants have been used for many years in the treatment of various diseases, including cancer. Centaurea solstitialis subsp. solstitialis is used in Turkish folk medicine. This ... -
Anticancer effect of the fruit and seed extracts of Momordica charantia L. (Cucurbitaceae) on human cancer cell lines
Güneş, Hatice; Alper, Mehlika; Çelikoğlu, Nevin (Pharmacotherapy Group, 2019)Purpose: To investigate anticancer effects of Momordica charantia L. (M. charantia) fruit and seed extracts on some cancer cell lines. Methods: Human cancer cell lines, including lung cancer (A549), breast cancer (MCF-7), ... -
Antioxidant Activity and Phenolic Composition of Ethanol Extracts of Momordica charantia and Datura stramonium
Alper, Mehlika; Özay, Cennet (KAHRAMANMARAS SUTCU IMAM UNIV REKTORLUGU, 2022)Medicinal plants in the world are natural antioxidant sources as they contain some secondary metabolites such as phenolic acids and flavonoids. Therefore, they are used to prevent or treat many diseases in many parts of ... -
Antiproliferative and antioxidant potential of methanol extracts of aerial parts of Colchicum boissieri and Colchicum balansae
Alper, Mehlika (Pamukkale University, 2022)The antiproliferative and antioxidant activities, and total phenolic, flavonoid, and tannin contents of methanol extracts obtained from the aerial parts of Colchicum boissieri and Colchicum balansae were investigated in ... -
Assessment of Antioxidant and Cytotoxic Activities and Identification of Phenolic Compounds of Centaurea solstitialis and Urospermum picroides from Turkey
Alper, Mehlika; Güneş, Hatice; Özay, Cennet; Mammadov, Ramazan (Instituto de Tecnologia do Parana, 2021)It is known that some genera of the Asteraceae family are commonly used in Turkish folk medicine. Several studies have investigated the biological effects of different extracts of Centaurea and Urospermum species, but ... -
Bioactivities of cry gene positive Bacillus thuringiensis (Berliner) (Bacillales: Bacillaceae) strains on Ephestia kuehniella Zeller, 1879 and Plodia interpunctella (Hubner, 1813) (Lepidoptera: Pyralidae)
Alper, Mehlika; Gunes, Hatice; Col, Bekir; Tunca, Hilal (Entomological Soc Turkey, Ege Univ, 2016)Bacillus thuringiensis is the bacterium most commonly used for biopesticide production due to parasporal crystal formation during its growth cycle. As a consequence of repeated use, B. thuringiensis biopesticides may cause ... -
Bioactivities of cry gene positive Bacillus thuringiensis (Berliner) (Bacillales: Bacillaceae) strains on Ephestia kuehniella Zeller, 1879 and Plodia interpunctella(Hübner, 1813) (Lepidoptera: Pyralidae)1,2
Alper, Mehlika; Güneş, Hatice; Çöl, Bekir; Tunca, Hilal (2016)Bacillus thuringiensis üreme döngüsü sırasında kristal oluşturması nedeniyle biyopestisit üretimi için en çok kullanılan bakteridir. Bacillus thuringiensis biyopestisitlerinin tekrarlayan kullanımları zararlılarda direnç ... -
Cytotoxic and Antioxidant Potential of Chloroform Extract of Holothuria tubulosa Gmelin, 1791
Doğangüneş, Müge; Türker, Ali; Güneş, Hatice; Alper, Mehlika (Springer, 2022)Abstract: Natural products are promising anticancer agents and antioxidants. The present study was aimed to evaluate the cytotoxic and antioxidant potential and the contents of phenolic compounds of a chloroform extract ... -
Determination of anticancer effects of Urospermum picroides against human cancer cell lines
Alper, Mehlika; Güneş, Hatice (2019)Plants continue to be a good source for developing effective anticancer agents. In this study, in vitro various biological effects of crude ethanolic extract from flowering parts of Urospermum picroides collected from the ... -
Distribution, occurrence of cry genes, and lepidopteran toxicity of native Bacillus thuringiensis isolated from fg tree environments in Aydın Province
Alper, Mehlika; Güneş, Hatice; Tatlıpınar, Arzu; Çöl, Bekir; Civelek, Hasan Sungur; Özkan, Cem; Poyraz, Burcu (2014)Bacillus thuringiensis (Bt) has a signifcant impact on biological pest control because of the insecticidal activity through its parasporal inclusion bodies (crystal proteins). Fig is an economically important plant in ... -
Distribution, occurrence of cry genes, and lepidopteran toxicity of native Bacillus thuringiensis isolated from fig tree environments in Aydin Province
Alper, Mehlika; Gunes, Hatice; Tatlipinar, Arzu; Col, Bekir; Civelek, Hasan Sungur; Ozkan, Cem; Poyraz, Burcu (Tubitak Scientific & Technical Research Council Turkey, 2014)Bacillus thuringiensis (Bt) has a significant impact on biological pest control because of the insecticidal activity through its parasporal inclusion bodies (crystal proteins). Fig is an economically important plant in ... -
Doxorubicin Release from Bovine Serum Albumin Microparticles
Gülsu, Aydan; Aslanpay, Mutlu Can; Alper, Mehlika; Güneş, Hatice (SPRINGER, 2022)Doxorubicin (Dox) is an anthracycline antibiotic and highly potent anticancer drug. However, its utility is often limited by severe side effects such as irreversible cardiotoxicity and reversible nephrotoxicity. In recent ... -
Evaluation of cytotoxic, apoptotic effects and phenolic compounds of sea cucumber Holothuria tubulosa (Gmelin, 1791) extracts
Alper, Mehlika; Gunes, Melek (Scientific Technical Research Council Turkey-Tubitak, 2020)This study aimed to investigate the potential cytotoxic effects and phenolic contents of aqueous (HTS) and methanolic (HTM) extracts of Holothuria tubulosa gathered from Mugla (Turkey) against different cancer cells for ... -
INVESTIGATION OF POTENTIAL ANTI-CANCER AND ANTI-INFLAMMATORY EFFECTS OF DATURA STRAMONIUM ETHANOLIC EXTRACTS AGAINST SELECTED HUMAN CANCER CELL LINES
Alper, Mehlika (Parlar Scientific Publications (P S P), 2019)In this study, the different biological properties particularly associated with anti-cancer and anti-inflammatory effects of the D. stramonium extracts from Edirne (Turkey) were examined for the first time. The ethanolic ... -
Paclitaxel Delivery by Cationic Gelatin Nanoparticles
Gülsu, Aydan; Kıllı, Büşra; Alper, Mehlika (WILEY-V C H VERLAG GMBH, 2022)Biodegradable polymeric nanoparticles have gained importance since they improve the therapeutic value of various water insoluble drugs and bioactive molecules by improving bioavailability, solubility and retention time. ... -
Potential cancer treatment effects of brusatol or eriodictyol combined with 5-fluorouracil (5-FU) in colorectal cancer cell
Ardil, buse; Alper, Mehlika (SPRINGER, 2022)Colorectal cancer is among the most frequently diagnosed cancers in patients today. In the treatment of this disease, combination or multicomponent therapy has been identified as a potential method to improve patient ...
