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An assessment of the protective effect of gonadotropin-releasing hormone agonist and antagonist on bleomycin-induced ovarian toxicity in rats
Atakul, Tolga; Tayyar, Ahter Tanay; Turan, Ozgur Deniz; Çelik, Serkan Yaşar; Yilmaz, Mustafa; Küçük, Mert; Demirci, Buket (Taylor & Francis Ltd, 2020)The aim of this study is to evaluate the effect of GnRH agonist or GnRH antagonist therapy on bleomycin-administered rats by examining ovarian follicle counts and AMH levels. A total of 30 female Wistar albino rats aged ... -
The effects of acitretin on ovarian reserve: An experimental study in rats
Güven, Münevver; Atakul, Tolga; Çelik, Serkan Yaşar; Yılmaz, Mustafa; Demirci, Buket (ERI ZUHREVI HASTALIKLAR DERNEGI, 2022)Background and Design: Acitretin is widely used on many dermatological diseases. No adequate studies have evaluated its effects on ovarian reserve. Thus, this expo m mental study aimed to investigate the possible effects ... -
Evaluation of oxaliplatin-induced pulmonary toxicity in rats
Kalemci, Serdar; Tanrıverdi, Özgür; Simsek, Abdullah; Aksun, Saliha; Celik, Ozgur I.; Barutca, Sabri; Demirci, Buket (Termedia Publishing House Ltd, 2019)Introduction: The mechanism of oxaliplatin (OXA) induced pulmonary toxi-city is not fully understood. Aim of the study: The present study was designed to investigate the pulmonary toxicity of OXA that has been reported in ... -
Evaluation of Protective Effects of Folinic Acid and Gonadotropin-Releasing Hormone Agonist and Antagonist Against Methotrexate Toxicity in Rats
Atagül, Tolga; Öner, Gökalp; Turan, Özgür Deniz; Çelik, Serkan Yaşar; Yılmaz, Mustafa; Yüksel, Hasan; Demirci, Buket (GALENOS YAYINCILIK, 2021)Abstract Objective: A single dose of the folic acid antagonist methotrexate (MIX) is commonly used in ectopic pregnancy. However, the safety of MTX therapy on the ovarian reserve is still controversial. This study aimed ...
