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In Vitro Effects of Propofol on Cytotoxic, Apoptotic and PI3K-Akt Signaling Pathway Genes on Brain Cancer Cells
Gökdoğan Edgünlü, Tuba; Avcı, Cigir Biray; Özateş, Neslihan Pınar; Göker Bağca, Bakiye; Karakaş Çelik, Sevim; Bölük, Aydın; Uğur, Bakiye (Bentham Science, 2021)Aim: It was aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism ... -
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
Arısu Naghavi, Esra; Tekeli, Senem; Uynaıkgil, Yiğit; Göker Bağca, Bakiye; Yiğittürk, Gürkan; Gökçe, Burak; Tomruk, Canberk; Çavuşoğlu, Türker; Biray Avcı, Çığır; Gündüz, Cumhur (Süleyman Demirel Üniversitesi, 2022)Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ...