Yazar "Kaplan, Mehmet" için listeleme
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Conservative vs Surgical Interventions for Umbilical Pilonidal Sinus: A Multicenter, Double-Blind, Prospective, Randomized Clinical Trial
Kaplan, Mehmet; Özcan, Önder; Kaplan, Fatma Çiğdem; Yalçın, Hüseyin Cahit; Salman, Bülent (Elsevier Science Inc, 2016)BACKGROUND: Umbilical pilonidal sinus (UPS) is one of the most neglected disorders, and there is still no clear consensus regarding optimal treatment of the disease. We therefore present our data from a prospective, ... -
Distal scar-to-midline distance in pilonidal Limberg flap surgery is a recurrence-promoting factor: A multicenter, case-control study
Kaplan, Mehmet; Özcan, Önder; Bilgiç, Ethem; Kaplan, Elif Tuğçe; Kaplan, Tuğba; Kaplan, Fatma Çigdem (Excerpta Medica Inc-Elsevier Science Inc, 2017)Background: The Limberg flap (LF) procedure is widely performed for the treatment of sacrococcygeal pilonidal sinus (SPS); however, recurrences continues to be observed. The aim of this study was to assess the relationship ... -
Does MiRNA gene expression predict gastric cancer stage and localization?
Özcan, Önder; Belli, Ahmet Korkut; Kayılıoğlu, Selami Ilgaz; Çelik, Özgür İlhan; Kaplan, Mehmet; Kara, Murat; Polat, Murat (2019)Gastric cancer comprises 10% of all cancers in the world and is rarely seen before the age of 30. Different genetic interactions or molecular changes like e-cadherin, P16, APC, c-erb B2, c-met, ras, or c-myc have been ... -
Laparoscopic organ-preserving gastric resection improves the quality of life in stromal tumor patients An observational study with 23 patients
Özcan, Önder; Kaplan, Mehmet; Yalçın, Hüseyin Cahit (Edizioni Luigi Pozzi, 2019)AIM: The aim of this study is to investigate whether organ preserving gastrectomy (OPG) would yield a greater ability to save more tissue and functions of the stomach and eventually provide better quality of postoperative ... -
MTUS1 tumor suppressor and its miRNA regulators in breast cancer
Kara, Murat; Kaplan, Mehmet; Bozgeyik, İbrahim; Özcan, Önder; Çelik, Özgür İlhan; Bozgeyik, Esra; Yumrutaş, Önder (Elsevier Science Bv, 2016)Breast cancer is major public health problem predominantly effects female population. Current therapeutic approaches to deal with breast cancer are still lack of effectiveness. Thus, identifying/developing novel strategies ... -
RUNX genes expressions in breast cancer and fibroadenoma
Ozcan, Onder; Belli, Ahmet Korkut; Kayilloglu, Selami Ilgaz; Donmez, Cem; Celik, Ozgur Ilhan; Kaplan, Mehmet; Polat, Murat (Derman Medical Publ, 2019)Aim: Many genes have been identified to control cell proliferation in human such as RUNX gene family. Mutations in these genes have been shown to be responsible for various cancer developments. Our aim in this study is to ... -
Upregulation of SIRT1 gene in gastric adenocarcinoma
Özcan, Önder; Belli, Ahmet Korkut; Çetin, Esin Sakallı; Kara, Murat; Çelik, Özgur İlhan; Kaplan, Mehmet; Polat, Murat (Aves, 2019)Background/Aims: SIRT1 gene overexpression is reportedly associated with cancer development, via the triggering of DNA repair impairment, and cell proliferation. The study aimed to investigate SIRT1 expression in patients ...