Browsing by Author "Erdoğan, Mümin Alper"
Now showing items 1-11 of 11
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Dexpanthenol reduces fibrosis and aids repair following nerve laceration and neurorrhaphy
Karahan, Gökhan; Kaya, Hüseyin; Eyceyurt, Recep Selçuk; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Spandidos Publications, 2021)The aim of the present study was to investigate the effect of dexpanthenol on nerve healing following neurorrhaphy in lacerated peripheral nerves. A total of 30 mature Sprague Dawley rats were used. Surgical sciatic nerve ... -
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia
Erdoğan, Mümin Alper; Kirazlar, Mehmet; Yiğittürk, Gürkan; Erbaş, Oytun (Springer, 2022)Alzheimer's disease (AD) is by far the most common cause of cognitive impairment in older adults. Current treatments are entirely focused on the symptoms of AD. A complex etiology for AD has been proposed recently, in which ... -
The Effects of Lipid Emulsion, Magnesium Sulphate and Metoprolol in Amitriptyline-Induced Cardiovascular Toxicity in Rats
Bora, Saylav; Erdoğan, Mümin Alper; Yigittürk, Gürkan; Erbaş, Oytun; Parlak, İsmet (Humana Press Inc, 2018)The aim of this study was to evaluate the effects of metoprolol, lipid emulsion and MgSO4 which can be recommended for prevention of long QT that is one of the lethal consequences of amitriptyline intoxication. Thirty ... -
An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
Taşkın, Banu; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Alper, Sibel; Erbaş, Oytun (Hindawi, 2021)Purpose. The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. Methods. The study was conducted on twenty-four male rats. ... -
The Healing Effect of Digoxin on Peripheral Nerve Damage and Its Relation to IL-17/IL-10
Gürkan, Gökhan; Erdoğan, Mümin Alper; Karahan, Gökhan; Kaya, Hüseyin; Yiğittürk, Gürkan (Turkish Neurosurgical Society, 2023)AIM: To demonstrate the curative effect of digoxin on peripheral nerve damage with its anti-inflammatory role on interleukin (IL)-17. MATERIAL and METHODS: The study was conducted with 30 male Sprague Dawley albino mature ... -
Lacosamide exhibits neuroprotective effects in a rat model of Parkinson's disease
Yigittürk, Gürkan; Bilal, Burçin; Kirazlar, Mehmet; Erdoğan, Mümin Alper; Erbaş, Oytun (Journal of Chemical Neuroanatomy, 2023)Background: Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that primarily affects the motor system. Although there are several treatments available to alleviate PD symptoms, there is ... -
Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats
Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun; Taşkıran, Dilek (TAYLOR & FRANCIS INC, 2021)Aim: Although the most common age-related neurodegenerative disease defined by memory loss is Alzheimer's disease (AD), only symptomatic therapies are present. A complex pathway for the AD pathogenesis that includes an ... -
The Protective Effects of Carvedilol on Diabetic Nephropathy in A Streptozotocin-Induced Diabetic Rat Model
Erdoğan, Mümin Alper; Yigittürk, Gürkan; Erbaş, Oytun (Wiley, 2019)[No abstract available] -
The Restorative Effect of Gallic Acid on the Experimental Sciatic Nerve Damage Model
Gürkan, Gökhan; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Korean Neurosurgical Society, 2021)Objective: Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is ... -
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
Bora, Ejder Saylav; Erdoğan, Arife; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Çakır, Adem; Erbaş, Oytun (URKISH ASSOC TRAUMA EMERGENCY SURGERY, 2022)BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ... -
Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study
Taşkıran, Emin; Erdoğan, Mümin Alper; Yiğittürk, Gürkan; Erbaş, Oytun (Humana Press Inc, 2019)Doxorubicin-induced (DXR) cardiomyopathy is a serious health issue in oncology patients. Effective treatment of this clinical situation still remains to be discovered. In this experimental animal study, we aimed to define ...
