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dc.contributor.authorBoran, Rukiye
dc.contributor.authorBaygar, Tuba
dc.contributor.authorSaraç, Nurdan
dc.contributor.authorUğur, Aysel
dc.date.accessioned2020-11-20T14:51:03Z
dc.date.available2020-11-20T14:51:03Z
dc.date.issued2018
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.urihttps://doi.org/10.3906/sag-1712-80
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TWprek1EQXpNdz09
dc.identifier.urihttps://hdl.handle.net/20.500.12809/1674
dc.description0000-0001-7676-542X;en_US
dc.descriptionWOS: 000435653900026en_US
dc.descriptionPubMed ID: 29916223en_US
dc.description.abstractBackground/aim: The potential inhibitory effects of Ankaferd Blood Stopper (ABS) against biofilm formation of oral microorganisms and its capacity for collagenase, hyaluronidase, and elastase inhibitions that have important roles in wound healing have been investigated. Materials and methods: The wound healing potential was determined by its inhibition ability on collagenase, hyaluronidase, and elastase enzyme activities and was evaluated via scratch wound healing assay on murine 3T3 fibroblasts. The antibiofilm activity was tested against eight oral microorganisms using the crystal violet staining method. Results: At 10% ABS successfully inhibited the biofilm formation of the tested microorganisms. Enzyme inhibition analysis revealed that 3% ABS significantly inhibited all three enzymes related to wound healing. The scratch assay showed that wound closure was faster than that of the control for the 3% ABS/plate. Conclusion: The findings of the present study indicated that ABS has effective wound healing potential with its strong antibiofilm activity against oral cavity microorganisms.en_US
dc.item-language.isoengen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnkaferd Blood Stopperen_US
dc.subjectEnzyme Inhibitionen_US
dc.subjectAntibiofilmen_US
dc.subjectWound Healingen_US
dc.titleAnkaferd Blood Stopper with antibiofilm potential successfully inhibits the extracellular matrix degradation enzymes and promotes wound healing of 3T3 fibroblasts in vitroen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Su Ürünleri Fakültesi, Su Ürünleri Avlama Ve İşleme Teknolojisi Bölümüen_US
dc.contributor.institutionauthorBaygar, Tuba
dc.contributor.institutionauthorSaraç, Nurdan
dc.identifier.doi10.3906/sag-1712-80
dc.identifier.volume48en_US
dc.identifier.issue3en_US
dc.identifier.startpage627en_US
dc.identifier.endpage634en_US
dc.relation.journalTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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