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dc.contributor.authorKasap, Burcu
dc.contributor.authorTürkcü, Ümmühani Özel
dc.contributor.authorAkbaba, Eren
dc.contributor.authorSarıyıldız, Behiye
dc.contributor.authorKüçük, Mert
dc.contributor.authorTurhan, Nilgün Öztürk
dc.contributor.authorÖzcan, Aykut
dc.date.accessioned2020-11-20T14:51:10Z
dc.date.available2020-11-20T14:51:10Z
dc.date.issued2018
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.urihttps://doi.org/10.1080/14767058.2017.1326097
dc.identifier.urihttps://hdl.handle.net/20.500.12809/1698
dc.descriptionWOS: 000430732400007en_US
dc.descriptionPubMed ID: 28462593en_US
dc.description.abstractPurpose: To investigate the relationships of TNF-related weak inducer of apoptosis (sTWEAK), a cytokine related to the TNF superfamily, its newly described soluble receptor sCD163, and the sTWEAK/sCD163 ratio with perinatal outcomes in women with first-trimester vaginal bleeding.Materials and methods: Seventy (41 threatened abortion and 29 control) gestational-age-matched (6-14weeks) pregnant women were included in the study. Antenatal complications (gestational diabetes, preeclampsia, intrauterine growth restriction, oligohydramniosis, polyhydramniosis), and perinatal outcomes (delivery mode, birth weight, delivery week) were recorded. Women with vaginal bleeding were divided into subgroups by pregnancy outcome (miscarriage or live birth) and subchorionic hematoma incidence. Statistical analyses were performed using the Student's t test, Mann-Whitney U test, chi-square test, and Pearson's correlation coefficient. p Values<.05 were considered as statistically significant.Results: There were no statistically significant differences in sTWEAK or sCD163 levels, in sTWEAK/sCD163 ratios, or antenatal complications between threatened abortion and control patients. Higher sTWEAK levels were significantly correlated with higher rates of miscarriage in the threatened abortion group (p=.014). sCD163 levels were significantly lower in the subchorionic hematoma subgroup of the threatened abortion group (p=.043).Conclusions: sTWEAK levels may predict the risk of miscarriage in pregnant women with first-trimester vaginal bleeding.en_US
dc.item-language.isoengen_US
dc.publisherTaylor & Francis Ltden_US
dc.item-rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectVaginal Bleedingen_US
dc.subjectPregnancyen_US
dc.subjectStweaken_US
dc.subjectScd163en_US
dc.subjectMiscarriageen_US
dc.titleThe predictive role of sTWEAK levels in pregnant women with first-trimester vaginal bleedingen_US
dc.item-typearticleen_US
dc.contributor.departmentMÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.contributor.institutionauthorKasap, Burcu
dc.contributor.institutionauthorTürkcü, Ümmühani Özel
dc.contributor.institutionauthorAkbaba, Eren
dc.contributor.institutionauthorSarıyıldız, Behiye
dc.contributor.institutionauthorKüçük, Mert
dc.contributor.institutionauthorTurhan, Nilgün Öztürk
dc.identifier.doi10.1080/14767058.2017.1326097
dc.identifier.volume31en_US
dc.identifier.issue13en_US
dc.identifier.startpage1715en_US
dc.identifier.endpage1719en_US
dc.relation.journalJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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