Yazar "0000-0002-9300-9324" için Dahili Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Evaluation of mTOR Activity in COPD Patients with Emphysema
Oral Tapan, Özge; Tapan, Utku; Edgünlü, Tuba; Doğan, Emrah (College of Physicians and Surgeons Pakistan, 2022)Objective: To evaluate the function of the mammalian target of the rapamycin (mTOR) pathway in chronic obstructive pulmonary disease (COPD) patients with emphysema. Study Design: Observational study. Place and Duration of ... -
Molecular and in silico analyses of SYN III gene variants in autism spectrum disorder
Barış, Remzi Oğuz; Şahin, Nilfer; Bilgiç, Ayşegül Demirtaş; Edgünlü, Tuba; Özdemir, Çilem (Springer Science and Business Media Deutschland GmbH, 2023)Background: Defects in neurotransmission and synaptogenesis are noteworthy in the pathogenesis of ASD. Synapsin III (SYN III) is defined as a synaptic vesicle protein that plays an important role in synaptogenesis and ... -
A study of the correlation between the serum Latexin levels and the mTORC subunits Raptor and Rictor in the molecular pathogenesis of chronic lymphocytic leukemia
Pektaş, Gökhan; Karakuş, Volkan; Çetin, Deniz; Edgünlü, Tuba (Turaz Bilim, 2021)Abstract: Hematopoietic stem cells (HSCs) ensure the lifelong production of blood cells throughout a lifetime. Latexin (Lxn) is thought to have a tumor suppressor role and endogenously down-regulate the number of HSCs via ... -
Vesicle trafficking with snares: a perspective for autism
Özdemir, Çilem; Şahin, Nilfer; Edgünlü, Tuba (Springer Science and Business Media B.V., 2022)Vesicle-mediated membrane traffic is the mechanism fundamental to many biological events, especially the release of neurotransmitters. The main proteins of the mechanism that mediates membrane fusion in vesicle-mediated ...