Erişim şekli için "info:eu-repo/semantics/openAccess" Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 96, listelenen: 41-60
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The effects of walnut supplementation on hippocampal NMDA receptor subunits NR2A and NR2B of rats
(Taylor & Francis Ltd, 2017)Objectives: Walnuts contain numerous selected dietary factors that have an impact on brain functions, especially learning and memory formation in the hippocampus. Hippocampal N-methyl D-aspartate receptors (NMDARs) are ... -
Ethical Assessment of Blank Consent Forms for Medical Interventions in a Training and Research Hospital in Turkey
(Aves, 2018)Objective: To assess ethical conformity of consent forms to the ethical standards used for medical interventions in a training and research hospital. Methods: In this study, the content of blank informed consent forms used ... -
Evaluation of the Vertebral Artery by 3D Digital Subtraction Angiography
(Soc Chilena Anatomia, 2014)The objective of the present study is to determine origin, entry level to the transverse foramen and diameter according to sex and side through 3D angiographic images of seventy-nine vertebral arteries obtained using DSA ... -
An Experimental Study: Benefits of Digoxin on Hepatotoxicity Induced by Methotrexate Treatment
(Hindawi, 2021)Purpose. The aim of the study is to examine the possible therapeutic effects of a known cardiac glycoside, digoxin, on a rat model of MTX-induced hepatotoxicity. Methods. The study was conducted on twenty-four male rats. ... -
Exploration of Potential miRNA Biomarkers and Prediction for Ovarian Cancer Using Artificial Intelligence
(MedGen, 2021)Ovarian cancer is the second most dangerous gynecologic cancer with a high mortality rate. The classification of gene expression data from high-dimensional and small-sample gene expression data is a challenging task. The ... -
Gene variants and serum levels of synaptic vesicle and presynaptic plasma membrane proteins in alcohol dependence and their relationship with impulsivity and temperament
(UNIV SAOPAULO, 2021)Background: Exocytosis-related gene variants have been suggested to be associated with externalizing behaviors. Objective: This study aimed to examine VAMP2 26 bp Ins\Del, synaptotagmin XI (Syt11) rs3820594 and 33-bp ... -
GPR30 Gene Polymorphisms Are Associated with Gynecomastia Risk in Adolescents
(Karger, 2015)Aim: The G protein-coupled receptor, GPR30, which is a third estrogen receptor, has been shown to mediate estrogenic effects on the essential features of human breast cancer cells. The aim of this study was to evaluate the ... -
Homozygous Ala65Pro Mutation with V89L Polymorphism in SRD5A2 Deficiency
(Galenos Yayincilik, 2016)Objective: Deficiency of steroid 5-alpha reductase type 2 (5 alpha RD2) is a rare autosomal recessive disorder caused by mutations in the SRD5A2 gene. A defect in the 5-alpha reductase enzyme, which ensures conversion of ... -
Hydroquinidine displays a significant anticarcinogenic activity in breast and ovarian cancer cells via inhibiting cell-cycle and stimulating apoptosis
(TUBITAK, 2023)Breast and ovarian cancers are women’s most commonly diagnosed cancers. Seeking an efficient anticarcinogenic compound is still a top priority regarding the aggressiveness of these cancers and the limited benefit of current ... -
Hydroxychloroquine/azithromycin treatment, QT interval and ventricular arrhythmias in hospitalised patients with COVID-19
(Wiley, 2021)Hydroxychloroquine (HCQ) and azithromycin (AZM) are widely used in off‐label treatment of novel coronavirus disease (COVID‐19). However, cardiac safety of these drugs is still controversial in COVID‐19. Therefore, we aimed ... -
Identifying Potential miRNA Biomarkers for Gastric Cancer Diagnosis Using Machine Learning Variable Selection Approach
(Frontiers Media S.A., 2022)Aim: This study aimed to accurately identification of potential miRNAs for gastric cancer (GC) diagnosis at the early stages of the disease. Methods: We used GSE106817 data with 2,566 miRNAs to train the machine learning ... -
Immunohistochemical Distribituon of COX-1, COX-2, and TGF beta-1 in the Duodenum of Rats Treated with Capsaicin
(Kafkas Univ, Veteriner Fakultesi Dergisi, 2016)The purpose of this study was to investigate the effects of capsaicin on the duodenal distribution of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and Transforming growth factor beta-1 (TGF beta-1) in rats. Rats were ... -
The impact of gender and academic achievement on the violation of academic integrity for medical faculty students, a descriptive cross-sectional survey study
(Bmc, 2019)Purpose: The aim of this study is to determine the characteristics of medical faculty students about violations of academic integrity. Method: From the whole population of the 572 students of the Mugla Sitki Kocman University ... -
The Important Witness of the Malaria Struggle in Turkey: Milasli Ismail Hakki and His Pamphlet Entitled "Who Knows What About Malaria?"
(Duzce Univ, 2018)Objective: One of the malaria struggle methods in Turkey was informing public and professionals by publications. The aim of this study was to assess malaria struggle works at first years of the Turkish republician era in ... -
Influence of Pinealectomy and Long-term Melatonin Administration on Inflammation and Oxidative Stress in Experimental Gouty Arthritis
(Springer, 2022)Gout is an inflammatory arthritis characterized by the deposition of monosodium urate (MSU) crystals in the joints or soft tissue. MSU crystals are potent inflammation inducers. Melatonin (MLT) is a powerful endogenous ... -
Integrative Analysis of Axolotl Gene Expression Data from Regenerative and Wound Healing Limb Tissues
(Nature Research, 2019)Axolotl (Ambystoma mexicanum) is a urodele amphibian endowed with remarkable regenerative capacities manifested in scarless wound healing and restoration of amputated limbs, which makes it a powerful experimental model for ... -
INVESTIGATION OF URSODEOXYCHOLIC ACID EFFECTS ON SIROLIMUS TREATED ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS
(Süleyman Demirel Üniversitesi, 2022)Objective The usage of mesenchymal stem cells (MSC) with immunosuppressive drugs after organ transplantation is becoming remarkable in clinical applications. However, the drugs negatively affect MSCs. Ursodeoxycholic acid ... -
Is losartan a promising agent for the treatment of type 1 diabetes-induced testicular germ cell apoptosis in rats?
(Springer Science and Business Media B.V., 2022)Background: Diabetes mellitus (DM) is common metabolic disease that poses a major risk to public health and fertility. Previous studies indicate that DM may cause male infertility by triggering oxidative stress and germ ... -
İnsan Endometriyum Epitel Hücrelerinde Farklı Kontrollü Ovaryan Hipersitümulasyonu Protokollerinin Eksozom Belirteci CD63 Üzerine Etkisi
(Celal Bayar Üniversitesi, 2022)Giriş ve Amaç: Eksozomlar; protein, mRNA ve miRNA’ları taşıyan ve hedefledikleri hücrelerde/dokularda fonksiyonel değişikliklere neden olan kargo sistemleridir. CD63, eksozomların tanımlanması ve izolasyonu için anahtar ... -
Kanser Tanısı Alan Çocuk/Ergenlerin Onay Sürecine ve Tedaviye Katılımlarının Değerlendirilmesi
(2016)Kanser gibi yaşamı tehdit eden hastalık durumunda hekimler arasında tıbbi gerçeğin hastaya söylenmesi eğilimi her ülkenin kendi ahlaksal, sosyal ve kültürel yapısına göre farklılık gösterebildiği gibi, ülkelerin sağlık ...